Liquid Biopsy for Bile Duct Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to test a new blood test that may help doctors detect signs of cancer recurrence or progression in individuals with cholangiocarcinoma, a type of cancer affecting the bile ducts. By analyzing blood samples and medical records, researchers aim to track treatment response and predict future outcomes. The trial seeks participants diagnosed with cholangiocarcinoma who are being considered for surgery to completely remove the cancer. As an unphased trial, this study offers participants the chance to contribute to groundbreaking research that could enhance future cancer care.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Why are researchers excited about this trial?
Researchers are excited about this trial because it explores a new method of monitoring cholangiocarcinoma, a type of bile duct cancer, using liquid biopsy. Unlike traditional treatments that rely heavily on imaging and invasive tissue biopsies to assess treatment response, this approach involves analyzing blood samples to detect cancer markers. This method is less invasive and could potentially provide real-time insights into how well a treatment is working, making it a game-changer in personalizing and improving patient care.
Who Is on the Research Team?
Nguyen H. Tran, MD
Principal Investigator
Mayo Clinic in Rochester
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pre-treatment
Collection of blood samples and archived tissue samples for baseline PUMA level assessment
Neoadjuvant Treatment
Participants receive neoadjuvant therapy and PUMA levels are monitored pre- and post-treatment
Surgical Intervention
Participants undergo surgical intervention and PUMA levels are assessed pre- and post-surgery
Follow-up
Participants are monitored for progression free survival and postoperative survival
What Are the Treatments Tested in This Trial?
Interventions
- Non-Interventional Study
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Patients undergo collection of blood samples and have their medical records reviewed on study. Patients also undergo collection of archived tissue samples on study.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Mayo Clinic
Lead Sponsor
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.