~97 spots leftby Jan 2026

Mindfulness-Based Stress Reduction for Chronic Pain (OPTIMUM Trial)

Palo Alto (17 mi)
Overseen byNatalia Morone, MD MS
Age: 18+
Sex: Any
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: N/A
Waitlist Available
Sponsor: Boston Medical Center
No Placebo Group

Trial Summary

What is the purpose of this trial?The purpose of this pragmatic clinical trial (PCT) research is to determine whether a group-visit approach modeled on Mindfulness-Based Stress Reduction can improve function for persons with chronic low back pain. This will be done by an embedded PCT within the evidence-based "OPTIMUM" (Optimizing Pain Treatment In Medical settings Using Mindfulness) program.

Eligibility Criteria

This trial is for adults over 18 with chronic low back pain lasting at least 3 months, experiencing pain on most days in the past half year. Participants must score ≥3 on the PEG scale, speak English, and be able to consent online or by phone. Excluded are those with recent severe symptoms, pregnancy, metastatic cancer, relatives of OPTIMUM study participants or non-patients of participating clinics.

Inclusion Criteria

I am 18 years old or older.
I have had lower back pain for at least 3 months, with pain on most days in the last 6 months.

Exclusion Criteria

My cancer has spread to other parts of my body.

Treatment Details

The trial tests if group medical visits using mindfulness-based stress reduction can improve function in people with chronic low back pain compared to usual care from their primary care provider (PCP). It's part of the 'OPTIMUM' program designed for such conditions.
2Treatment groups
Experimental Treatment
Active Control
Group I: Mindfulness Pain Program + Usual PCP CareExperimental Treatment2 Interventions
Participants will undergo 8 weekly 90 minute sessions of Mindfulness-Based Stress Reduction in addition to receiving usual PCP care for chronic lower back pain.
Group II: Usual PCP CareActive Control1 Intervention
Participants will receive usual PCP care for chronic lower back pain.

Find a clinic near you

Research locations nearbySelect from list below to view details:
Boston Medical CenterBoston, MA
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Who is running the clinical trial?

Boston Medical CenterLead Sponsor
National Center for Complementary and Integrative Health (NCCIH)Collaborator

References