Fractional Radiofrequency vs Fractional Photothermolysis for Acne Scars

N/A

Waitlist Available

Led By Murad Alam, MD

Research Sponsored by Northwestern University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 hour at baseline and week 16

Awards & highlights

No Placebo-Only Group

Summary

This trial will compare two treatments for improving the appearance of acne scars.

Who is the study for?

This trial is for adults with specific types of acne scars on their face who are in good health and can give informed consent. It's not for those allergic to local anesthetics like lidocaine, have eyelid disfigurements, recent facial treatments (injectables or resurfacing), pregnant or breastfeeding individuals, recent isotretinoin users, or a history of abnormal scarring.

What is being tested?

The study compares two acne scar treatments: ePrime fractional radiofrequency and Fraxel (1550-nm fractional photothermolysis). Participants will receive one treatment on each side of their face to see which improves the appearance of acne scars better.

What are the potential side effects?

Potential side effects may include skin redness, swelling, pain at the treatment site, temporary changes in skin coloration, blistering and bruising. Rarely there could be scarring from the treatment itself.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 hour at baseline and week 16

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 hour at baseline and week 16

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 hour at baseline and week 16 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in best overall cosmetic appearance (right side or left side better)rated by a blinded dermatologist from baseline to week 16

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Active Control

Group I: 1550-nm Fractional PhotothermolysisActive Control1 Intervention

Subjects will be randomly assigned to receive fractional radiofrequency treatment to either the right or left side of the face and the contralateral side will receive 1550-nm fractional photothermolysis. Subjects will receive treatments at baseline, week 4, and week 8 for a total of three treatments. Follow up visits will take place at week 16, two months following the last treatment visit.

Group II: Fractional RadiofrequencyActive Control1 Intervention

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