Silicone Ointment for Wound Healing

Recruiting in Palo Alto (17 mi)

Overseen byYan Lee, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Yale University

Trial Summary

What is the purpose of this trial?Optimal scar healing is of great importance to patients, especially following surgery of the head and neck. This study evaluates the effectiveness of preoperative silicone ointment in wound healing in head and neck surgeries.

Eligibility Criteria

This trial is for individuals scheduled for non-emergency head or neck surgery due to benign conditions, who can follow the study's procedures and have given informed consent. It excludes those on chronic steroids/immunosuppressants, with skin integrity issues like severe acne or psoriasis, allergies to silicone ointment components, active cancer at the surgical site, or need for post-surgery tracheostomy.

Inclusion Criteria

Provision of signed and dated informed consent form

I am scheduled for a non-urgent head or neck surgery for a non-cancerous condition.

Able to comply with all study procedures for the duration of the study

Exclusion Criteria

I have had radiation therapy on the area where I will have surgery.

I have an active cancer at the time of my surgery.

I am currently taking steroids or other medications that weaken my immune system.

+6 more

Participant Groups

The study tests if applying a silicone ointment before surgery can improve wound healing in patients undergoing head and neck surgeries. Participants will receive either the silicone ointment or a placebo without active ingredients before their procedure.

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Preoperative silicone ointmentExperimental Treatment1 Intervention

Participants will apply silicone ointment to the area where the surgical incision will be made, twice daily for 2-6 weeks prior to their scheduled surgery.

Group II: Preoperative placebo ointmentPlacebo Group1 Intervention

Participants will apply placebo ointment to the area where the surgical incision will be made, twice daily for 2-6 weeks prior to their scheduled surgery.