Fish Oil for Cold Exposure

Overseen By Timothy D Mickleborough, PhD

Age: 18 - 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Recruiting

Sponsor: Indiana University

Trial Summary

What is the purpose of this trial?

This trial will test if taking fish oil supplements helps healthy adults aged 18-40 manage cold better by affecting their body's heat production and blood flow. Fish oil supplements, rich in omega-3 fatty acids, have been studied for various health benefits including cardiovascular health, glucose metabolism, and lipid profile improvements.

Research Team

Timothy D Mickleborough, PhD

Principal Investigator

Indiana University

Eligibility Criteria

This trial is for active men and women aged 18-40 with a BMI of 18.5 to 24.9, who don't smoke or have bleeding disorders, immune/autoimmune diseases, metabolic or heart disease, hypertension, renal or neurological issues. They shouldn't be taking SSRIs, ADHD meds, painkillers regularly; consume fish oil supplements or more than one fish meal weekly; have rectal disorders; be pregnant; or have high blood pressure/pulse rate.

Inclusion Criteria

Your body mass index (BMI) falls within the healthy range of 18.5 to 24.9 kg/m2.

Male and female, between the ages of 18 to 40 years

You are physically active according to the International Physical Activity Questionnaire (IPAQ) and the Physical Activity Readiness Questionnaire (PAR-Q+).

Exclusion Criteria

You have a history of problems with bleeding or blood clotting.

You have a history of smoking or using tobacco products.

You have a history of high cholesterol.

Treatment Details

Interventions

• Fish Oil (Omega-3 Fatty Acids)
• Placebo (Behavioural Intervention)

Trial Overview The study tests if fish oil supplements can influence brown fat activity and the body's response to cold exposure compared to a placebo. Participants will experience cold conditions while their shivering responses, thermal comfort levels and skin blood flow are monitored.

Participant Groups

Group I: Fish Oil (Omega-3 Fatty Acids) Experimental Treatment 1 Intervention

15 subjects will ingest 6 capsules of fish oil of per day for 12 weeks

Group II: Olive Oil Placebo Group 1 Intervention

15 subjects will ingest 6 capsules of olive oil per day for 12 weeks

Who Is Running the Clinical Trial?

Indiana University

Lead Sponsor

Trials

1,063

Recruited

1,182,000+