~55 spots leftby Mar 2026

Cologuard vs FIT for Colorectal Cancer

Recruiting in Palo Alto (17 mi)
Overseen byJoshua Demb, PhD
Age: 18 - 65
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: University of California, San Diego
No Placebo Group

Trial Summary

What is the purpose of this trial?The objective of this pilot study is to compare the effectiveness of mailed outreach of two stool based tests, Cologuard and the fecal immunochemical test (FIT) in screening eligible adults ages 45-49 receiving care at the University of California San Diego Health system.

Eligibility Criteria

This trial is for adults aged 45-49 who are not current with colorectal cancer (CRC) screening, have a primary care provider at UCSD Health, have had a health visit within the last year, and live in San Diego or Imperial County. They must also be insured.

Inclusion Criteria

You have not had the recommended screening for colorectal cancer.
I am aged 45-49 and have a primary care provider at UCSD Health.
You have health insurance, whether it's from a private or public provider.
+2 more

Participant Groups

The study is testing the effectiveness of two stool-based CRC screening methods by mailing them to participants: Cologuard and the fecal immunochemical test (FIT). It aims to see which one works better for people receiving care at UCSD Health.
2Treatment groups
Experimental Treatment
Active Control
Group I: Mailed Cologuard OutreachExperimental Treatment1 Intervention
Receipt of mailed Cologuard test for colorectal cancer screening to be completed and returned by participant. If test is negative, participant will be advised to undergo another test in 3 years. If test is positive, participant will be advised to schedule colonoscopy for further testing.
Group II: Mailed Fecal immunochemical test OutreachActive Control1 Intervention
Receipt of mailed FIT for colorectal cancer screening to be completed and returned by participant. If test is negative, participant will be advised to undergo another test in 1 year. If test is positive, participant will be advised to schedule colonoscopy for further testing.

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
University of California San DiegoLa Jolla, CA
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Who Is Running the Clinical Trial?

University of California, San DiegoLead Sponsor

References