~36 spots leftby Sep 2025

Survivor & Provider Activation for Colorectal Cancer Screening

(ASPIRES Trial)

Recruiting in Palo Alto (17 mi)
+3 other locations
The University of Chicago
Overseen byKaren Kim, MD, MS
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: University of Chicago
No Placebo Group

Trial Summary

What is the purpose of this trial?The primary purpose of this study is to assess the best method for encouraging high-risk cancer survivors to get screened for colorectal cancer at the recommended age.

Eligibility Criteria

This trial is for high-risk cancer survivors without a family history of colorectal cancer, who were treated with certain types of radiation, and haven't had recent colorectal screenings. Participants must have a smartphone, be part of the Childhood Cancer Survivor Study, speak English, and live in the U.S.

Inclusion Criteria

Enrolled on the Childhood Cancer Survivor Study
My family has no history of colorectal cancer.
I have received radiation therapy to my abdomen, pelvis, spine, or whole body.
+3 more

Exclusion Criteria

Do not reside in the United States
I do not speak English.

Participant Groups

The ASPIRES study is testing different methods to motivate these survivors to undergo colorectal cancer screening. It compares no intervention (control) with strategies aimed at activating patients directly or through their primary care providers.
3Treatment groups
Experimental Treatment
Group I: Group1: Control (C)Experimental Treatment1 Intervention
Electronic educational materials (C).
Group II: Group 3: Patient Activation and PCP Activation (PA + PCP)Experimental Treatment3 Interventions
C + PA + PCP activation (PA+PCP) with physician materials about colorectal cancer risk in this population
Group III: Group 2: Patient Activation (PA)Experimental Treatment2 Interventions
C + patient activation (PA) consisting of interactive tailored text messages with links to videos and resources

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
St. Jude Children's Research HospitalMemphis, TN
Memorial Sloan Kettering Cancer CenterNew York, NY
University of ChicagoChicago, IL
Columbia UniversityNew York, NY
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Who Is Running the Clinical Trial?

University of ChicagoLead Sponsor
Penn State UniversityCollaborator
National Cancer Institute (NCI)Collaborator
St. Jude Children's Research HospitalCollaborator
Memorial Sloan Kettering Cancer CenterCollaborator
Columbia UniversityCollaborator
Hunter College of City University of New YorkCollaborator
The Hospital for Sick ChildrenCollaborator
Duke UniversityCollaborator

References