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Does Routine Submucosal Injection Improve Complete Resection of 4-20 mm Neoplastic Colorectal Polyps?

N/A
Waitlist Available
Led By Daniel von Renteln, MD
Research Sponsored by Centre hospitalier de l'Université de Montréal (CHUM)
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* Signed consent form; aged 45-80 years old, indication to undergo a colonoscopy
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 14 days after the initial procedure
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing a new method to improve the removal of small growths in the colon by injecting a fluid under them before cutting them out. It targets patients aged 45-80 undergoing colonoscopy to reduce the risk of colorectal cancer. The fluid helps lift the growths for easier and more complete removal.

Eligible Conditions
  • Colorectal Cancer

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~14 days after the initial procedure
This trial's timeline: 3 weeks for screening, Varies for treatment, and 14 days after the initial procedure for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Incomplete resection rate (IRR)
Secondary study objectives
Delayed bleeding complications
Immediate bleeding complications
Incomplete resection of colorectal polyps
+2 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Cold snare polypectomy with a submucosal injectionExperimental Treatment1 Intervention
The procedure will include a cold snare polypectomy with a submucosal injection done prior to the resection.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Cold snare polypectomy in conjunction with a submucosal injection
2021
N/A
~430

Find a Location

Who is running the clinical trial?

Centre hospitalier de l'Université de Montréal (CHUM)Lead Sponsor
377 Previous Clinical Trials
131,091 Total Patients Enrolled
Daniel von Renteln, MDPrincipal InvestigatorCentre hospitalier de l'Université de Montréal (CHUM)
3 Previous Clinical Trials
932 Total Patients Enrolled
~87 spots leftby Dec 2025
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