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Procedure

Trial of MR-guided Focused Ultrasound (MRgFUS) Bilateral Capsulotomy for the Treatment of Refractory Obsessive-compulsive Disorder (OCD)

N/A
Waitlist Available
Led By Nir Lipsman, MD, PhD
Research Sponsored by Sunnybrook Health Sciences Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing a new treatment using focused ultrasound waves guided by MRI for patients with OCD who haven't responded to other treatments. The treatment works by heating and destroying a small part of the brain to change its activity.

Eligible Conditions
  • Obsessive-Compulsive Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Incidence of Treatment-Emergent Adverse Events [Safety]
Secondary study objectives
Clinically meaningful reduction in symptoms [Efficacy]

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Focused UltrasoundExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Focused Ultrasound
2012
Completed Phase 2
~50

Find a Location

Who is running the clinical trial?

Sunnybrook Health Sciences CentreLead Sponsor
680 Previous Clinical Trials
1,565,854 Total Patients Enrolled
9 Trials studying Obsessive-Compulsive Disorder
798 Patients Enrolled for Obsessive-Compulsive Disorder
Hotchkiss Brain Institute, University of CalgaryOTHER
11 Previous Clinical Trials
2,420 Total Patients Enrolled
1 Trials studying Obsessive-Compulsive Disorder
120 Patients Enrolled for Obsessive-Compulsive Disorder
Nir Lipsman, MD, PhDPrincipal InvestigatorSunnybrook Health Sciences Centre, Sunnybrook Research Institute
3 Previous Clinical Trials
22 Total Patients Enrolled
Zelm Kiss, MD, PhDPrincipal InvestigatorUniversity of Calgary
~1 spots leftby Dec 2025
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