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Salivary Biomarkers for Concussion Recovery

N/A
Waitlist Available
Led By Praveen Arany, DDS, PhD
Research Sponsored by State University of New York at Buffalo
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 28 days
Awards & highlights
No Placebo-Only Group

Summary

This trial tests if exercise can help concussed adolescents recover by tracking changes in specific markers in their saliva. The study involves giving them specific exercise routines and measuring these markers to see if they indicate recovery.

Eligible Conditions
  • Concussion

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~28 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 28 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Persistent Post Concussion Symptoms (PPCS) (Yes/No)

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: Concussed Participants Group 2Experimental Treatment1 Intervention
Low Volume Group
Group II: Concussed Participants Group 1Experimental Treatment1 Intervention
High Volume Group
Group III: Healthy controls Group 1Active Control1 Intervention
High Volume Group
Group IV: Healthy Controls Group 2Active Control1 Intervention
Low Volume Group
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
High Volume Aerobic Exercise
2022
N/A
~60
Low Volume Aerobic Exercise
2022
N/A
~60

Find a Location

Who is running the clinical trial?

National Center for Advancing Translational Sciences (NCATS)NIH
374 Previous Clinical Trials
409,222 Total Patients Enrolled
State University of New York at BuffaloLead Sponsor
268 Previous Clinical Trials
51,581 Total Patients Enrolled
John Leddy, MDStudy DirectorUniversity at Buffalo
3 Previous Clinical Trials
396 Total Patients Enrolled
Mohammad Nadir, MD, PhDStudy DirectorUniversity at Buffalo
Praveen Arany, DDS, PhDPrincipal InvestigatorUniversity at Buffalo
Barry Willer, PhDStudy ChairUniversity at Buffalo
~16 spots leftby Dec 2025
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