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CT-FIRST: Cardiac Computed Tomography Versus Stress Imaging For Initial Risk STratification (CT-FIRST Trial)

N/A
Waitlist Available
Led By Todd C. Villines, M.D.
Research Sponsored by Walter Reed Army Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
No Placebo-Only Group

Summary

In patients with chest pain or shortness of breath who are referred for stress imaging tests (either stress echocardiography or stress nuclear testing), the investigators seek to compare impact of using cardiac CT scans of the heart arteries to the stress test that their doctors ordered.

Eligible Conditions
  • Coronary Artery Disease
  • Chest Pain
  • Stress Test

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Cardiac CT ArmExperimental Treatment1 Intervention
Patients referred for stress imaging due to complaints consistent with possible angina, randomized to receive an additional cardiac CT scan.
Group II: No CT ArmActive Control1 Intervention
Patients with symptoms consistent with possible angina, randomized to receive the type of stress imaging test ordered by their physician.

Find a Location

Who is running the clinical trial?

Walter Reed Army Medical CenterLead Sponsor
69 Previous Clinical Trials
20,699 Total Patients Enrolled
Todd C. Villines, M.D.Principal InvestigatorWalter Reed Army Medical Center
~13 spots leftby Dec 2025