Exercise Training for Heart Disease
(EXCEED2 Trial)

Recruiting in Palo Alto (17 mi)

Overseen ByJennifer Reed, PhD

Age: 18+

Sex: Female

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Ottawa Heart Institute Research Corporation

No Placebo Group

Approved in 1 jurisdiction

Trial Summary

What is the purpose of this trial?This study will compare the effects of two different types of training on exercise capacity in women with coronary heart disease (CHD). Participants will be randomized into either the virtual high-intensity interval training (HIIT) or the virtual moderate-to-vigorous intensity continuous training (MICT). After randomization, patients will exercise twice a week, for 12 weeks. The sessions will be conducted virtually. Patients will undergo a maximal exercise test, cardiometabolic indicators (height (cm), body mass (kg), body composition (%), waist circumference (cm) and, resting blood pressure) and complete questionnaires about quality of life, mental health, self-determined motivation, self-efficacy and enjoyment.

Eligibility Criteria

This trial is for women with coronary heart disease (CHD) who are interested in participating in a virtual exercise program. The study requires participants to train twice a week for 12 weeks, but specific inclusion and exclusion criteria details were not provided.

Inclusion Criteria

I can read and understand English or French.

I am a woman who had a heart procedure or event at least 4 weeks ago.

Patient is able to perform a symptom limited CPET

Exclusion Criteria

Patient currently participating in routine exercise training (>2x/week)

I have severe heart or lung conditions.

I am not willing to be assigned randomly to high-intensity or moderate-intensity exercise.

+3 more

Participant Groups

The study is testing the effectiveness of two different virtual exercise programs: high-intensity interval training (HIIT) and moderate-to-vigorous intensity continuous training (MICT). Women will be randomly assigned to one of these programs to see which is better at improving exercise capacity and heart health.

2Treatment groups

Experimental Treatment

Group I: standard care + moderate-intensity continuous exercise trainingExperimental Treatment1 Intervention

2 days/week Warm-up: 60-70% peak HR - 10min Training: 70-85% peak HR - 35min Cool-down: 60-70% peak HR - 15min

Group II: standard care + high-intensity interval trainingExperimental Treatment1 Intervention

2 days/week Warm-up: 60-70% peak HR - 10min Training: 85-95% peak HR - 25 minutes (4x4-minutes of high-intensity intervals interspersed with 3 minutes of low-intensity intervals) Cool-down: 60-70% peak HR - 10min