The DISCOVER INOCA Prospective Multi-center Registry
(DISCOVER INOCA Trial)

Recruiting in Palo Alto (17 mi)

+9 other locations

Overseen byAlexandra Lansky, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Recruiting

Sponsor: Yale University

No Placebo Group

Trial Summary

What is the purpose of this trial?

The overall objective of this multi-center registry is to identify specific phenotypes of INOCA with both an anatomic evaluation (coronary angiography and intravascular imaging) and physiologic assessment with the Abbott Coroventis Coroflow Cardiovascular System, and to determine long-term outcomes.

Research Team

Samit Shah, MD, PhD

Principal Investigator

Yale University Medical School

Alexandra Lansky, MD

Principal Investigator

Yale University Medical School

Eligibility Criteria

Inclusion Criteria

Suspected ischemic heart disease and is referred to undergo clinically indicated invasive coronary angiography

No obstructive coronary artery disease (CAD) as defined by operator visual assessment with (1) angiographically normal coronary arteries OR (2) non-obstructive CAD with angiographic stenosis < 50%, or greater than or equal to 50 but < 70% with FFR greater than or equal to 0.81 or RFR greater than or equal to 0.90

Willing to comply with specified follow-up evaluations. The participant or legally authorized representative has been informed of the nature of the study, agrees to its provisions, and has been provided written informed consent approved by the appropriate Institutional Review Board (IRB) or Ethics Committee (EC)