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Air Filtration and Ventilation
Air Filtration + Ventilation for COVID-19
N/A
Waitlist Available
Led By Abraar Karan, MD
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 7 days
Awards & highlights
No Placebo-Only Group
Summary
This trial tests if using box-fans with filters and better ventilation can reduce spread of Covid19 in homes with an infected person.
Who is the study for?
This trial is for households with a confirmed case of COVID-19 and at least three other people living together. Eligible homes must not have had the positive test result more than two days ago, expect most members to be present over the next week, and can't already have half or more members likely infected.
What is being tested?
The study tests if using box-fans with high-efficiency filters alongside guidance on improving home ventilation can prevent COVID-19 from spreading to others in the same household as someone who's infected.
What are the potential side effects?
There are no direct medical side effects from participating in this trial since it involves non-invasive interventions like air filtration and ventilation rather than medications.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 7 days
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~7 days
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Incidence of Covid19
Secondary study objectives
Average CO2 levels
Incidence of new upper respiratory symptoms
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: InterventionExperimental Treatment3 Interventions
Families are provided with one filtration fan unit per room in their home (and one for the index case; if the family lives in a studio, they would receive 2 units). Investigators will advise families on ventilation improvements in their home. Investigators will provide an instructional pamphlet that describes how the fans work and the importance of ventilation. Investigators will follow-up on day 3-4 to check in and run through a checklist to ensure the fans are working and ventilation improvements are being attempted. Investigators will give families a CO2 monitor to measure average CO2 levels in the home. Investigators will test family members at day 0-1 for baseline testing; and again on day 7 for assessing secondary transmission among susceptible contacts.
Group II: ControlActive Control1 Intervention
No intervention will be administered in this arm. Investigators will give families a CO2 monitor to measure average CO2 levels in the home. Investigators will provide a link to the basic CDC isolation guidelines which would be part of standard of care. Investigators will test family members at day 0-1 for baseline testing; and again on day 7 for assessing secondary transmission among susceptible contacts.
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Who is running the clinical trial?
National Institute of Allergy and Infectious Diseases (NIAID)NIH
3,336 Previous Clinical Trials
5,382,634 Total Patients Enrolled
Stanford UniversityLead Sponsor
2,491 Previous Clinical Trials
17,519,012 Total Patients Enrolled
Yvonne Maldonado, MDStudy DirectorStanford University
2 Previous Clinical Trials
2,148 Total Patients Enrolled
Abraar Karan, MDPrincipal InvestigatorStanford University
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Eligibility Criteria:
This trial includes the following eligibility criteria:- There are at least three other people living in the same house as the person being studied.If the positive test result was more than 2 days agoYou live with others in the same house or apartment, not in a separate room.If more than half of the people living in your home are believed to already have the infection.If there are usually less than 3 people in your house for most of the next 7 days
Research Study Groups:
This trial has the following groups:- Group 1: Intervention
- Group 2: Control
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.