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Group A for Coronavirus

N/A
Recruiting
Led By Ariel Graff, MD, PhD
Research Sponsored by Centre for Addiction and Mental Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at screening, baseline and at 3-month follow-up
Awards & highlights

Summary

Over one million Canadians have been infected by COVID-19. Many people who have been infected by COVID-19 experience negative mental symptoms, such as "brain fog" and fatigue. For many of these people, they continue to feel these negative mental symptoms even after recovering from COVID-19. However, scientists still do not know how COVID-19 harms the human brain and causes these mental problems. Our goal is to use advanced brain imaging to determine whether people who have been infected with COVID-19 show damage in their brain. We hope that this information will help doctors determine what treatments should be provided to help people who are suffering from continuing mental problems after being infected with COVID-19.

Eligible Conditions
  • Coronavirus
  • Long COVID Syndrome
  • Post-COVID Syndrome

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at screening, baseline and at 3-month follow-up
This trial's timeline: 3 weeks for screening, Varies for treatment, and at screening, baseline and at 3-month follow-up for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Presence and Severity of CNS and PASC Symptoms
Synaptic Density (PET Scan)
Secondary outcome measures
Biomarker Measures
Changes in Quality of Life
Cognitive, Emotional, Motor and Sensation Measures

Trial Design

3Treatment groups
Experimental Treatment
Group I: Group CExperimental Treatment1 Intervention
A control group of persons not previously infected with COVID-19.
Group II: Group BExperimental Treatment1 Intervention
Persons previously infected with COVID-19 without CNS-PASC symptoms within 6 months of recovery
Group III: Group AExperimental Treatment1 Intervention
Persons previously infected with COVID-19 experiencing CNS-PASC within 6 months of recovery

Find a Location

Who is running the clinical trial?

Sunnybrook Health Sciences CentreOTHER
671 Previous Clinical Trials
1,564,578 Total Patients Enrolled
Centre for Addiction and Mental HealthLead Sponsor
366 Previous Clinical Trials
82,279 Total Patients Enrolled
Ariel Graff, MD, PhDPrincipal InvestigatorCentre for Addiction and Mental Health
2 Previous Clinical Trials
166 Total Patients Enrolled
~4 spots leftby Dec 2024
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