Cognitive Behavioral Therapy for Anxiety and Depression in Autism

Recruiting in Palo Alto (17 mi)

Age: < 18

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Baylor College of Medicine

No Placebo Group

Approved in 3 Jurisdictions

Trial Summary

What is the purpose of this trial?

This study tests the effectiveness of a transdiagnostic cognitive behavioral therapy for autistic youth with anxiety and/or depression.

Eligibility Criteria

This trial is for autistic adolescents aged 12-17 with significant anxiety and/or depression, based in Texas. They must have a diagnosis of autism confirmed by specific assessments and primary issues with anxiety or depression. A parent must participate, no current psychotherapy for these conditions, stable medication use, and sufficient English skills are required.

Inclusion Criteria

The child meets criteria for autism spectrum disorder using evidence-based assessment approaches (e.g., Autism Diagnostic Observation Schedule-Second Edition; Childhood Autism Rating Scale-Second Edition)

Anxiety/depressive disorder is the primary presenting problem as determined by administration of the Mini International Neuropsychiatric Interview

One parent/guardian is able and willing to participate

Exclusion Criteria

My child has been diagnosed with a psychotic or conduct disorder.

The child has limited verbal communication abilities

My child urgently needs help for severe thoughts of harming themselves or others.

Participant Groups

The study is examining the impact of transdiagnostic cognitive behavioral therapy (CBT) on autistic youth with anxiety or depression compared to usual treatment methods. It aims to see if this tailored CBT approach can effectively reduce symptoms across both conditions.

Group I: Transdiagnostic cognitive behavioral therapy Experimental Treatment 1 Intervention

Group II: Treatment as usual Active Control 1 Intervention

Transdiagnostic Cognitive Behavioral Therapy is already approved in United States, European Union, Canada for the following indications:

🇺🇸 Approved in United States as Cognitive Behavioral Therapy for:

• Post-Traumatic Stress Disorder (PTSD)
• Anxiety Disorders

🇪🇺 Approved in European Union as Cognitive Behavioral Therapy for:

• Post-Traumatic Stress Disorder (PTSD)
• Anxiety Disorders
• Depression

🇨🇦 Approved in Canada as Cognitive Behavioral Therapy for:

• Post-Traumatic Stress Disorder (PTSD)
• Anxiety Disorders

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

Baylor Psychiatry Clinic Houston, TX

Who Is Running the Clinical Trial?

Baylor College of Medicine Lead Sponsor

Texas Higher Education Coordinating Board Collaborator

References