Trial Summary
What is the purpose of this trial?The purpose of this study is to assess the low-intensity focused ultrasound pulsation (LIFUP) neuromodulation on emotion processing in healthy individuals, and to assess the overall safety of the LIFUP to stimulate or inhibit brain activity in healthy volunteers.
Eligibility Criteria
This trial is for right-handed, healthy individuals who are not on drugs or psychotropic medications and have no chronic medical, psychiatric, or neurological illnesses. Women cannot be pregnant or nursing. Participants must also be comfortable with MRI scans and free from claustrophobia.Inclusion Criteria
Must be healthy (without medical, neurological, psychiatric illness)
Must be psychotropic medication free (≥ 14 days)
Must be illicit drug-free at the time of scanning as appropriate (verified by negative urine drug screen)
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Exclusion Criteria
Must not have ongoing, chronic, or relapsing/remitting medical, psychiatric,or neurological illness as determined by a combination of history, medical record, and/or examination.
Females must not be pregnant or nursing
You cannot be claustrophobic.
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Participant Groups
The study is testing the effects of a technique called LIFUP sonication to the amygdala on emotion processing in healthy people. It aims to understand how this low-intensity focused ultrasound can stimulate or inhibit brain activity safely.
1Treatment groups
Experimental Treatment
Group I: LIFUP sonication to the amygdalaExperimental Treatment1 Intervention
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
The University of Texas Health Science Center at HoustonHouston, TX
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Who Is Running the Clinical Trial?
The University of Texas Health Science Center, HoustonLead Sponsor