Digital Intervention for Depression and Cannabis Use

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Massachusetts General Hospital

No Placebo Group

Trial Summary

What is the purpose of this trial?The purpose of this study is to examine the feasibility, acceptability, and preliminary efficacy of a digital intervention for co-occurring cannabis use and depression. Participants will be randomized to complete Amplification of Positivity - Cannabis Use (AMP-C) or symptom tracking. The main outcomes will include participant acceptability and usability ratings, completion rates and compliance, positive affect, substance use, and depression severity.

Eligibility Criteria

This trial is for individuals with Major Depressive Disorder and Cannabis Use Disorder. Participants should be experiencing depression alongside cannabis abuse issues but not have other psychiatric conditions that could interfere with the study.

Inclusion Criteria

Resides in the United States

I am 18 years old or older.

Current elevated anhedonia, as indicated by the PHQ-9

+5 more

Exclusion Criteria

Active suicidal ideation or intent based on the Columbia-Suicide Severity Rating Scale

History of a psychotic disorder or bipolar disorder type I/II

I am currently seeing a therapist or counselor.

+1 more

Participant Groups

The study tests a digital program called Amplification of Positivity - Cannabis Use (AMP-C) against simple symptom tracking to see which helps more with mood and reducing cannabis use. People will be randomly assigned to one of these two approaches.

2Treatment groups

Experimental Treatment

Active Control

Group I: Amplification of Positivity - Cannabis Use (AMP-C)Experimental Treatment1 Intervention

Group II: Symptom TrackingActive Control1 Intervention