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Repetitive Transcranial Magnetic Stimulation

Intermittent Theta Burst Stimulation (form of repetitive transcranial magnetic stimulation) given in an accelerated form for Major Depressive Disorder

N/A
Waitlist Available
Led By Robyn Waxman
Research Sponsored by Ontario Shores Centre for Mental Health Sciences
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during and after each rtms treatment during acute treatment and up to a week after treatment
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing a magnetic pulse therapy to stimulate the brain for patients with severe depression who haven't responded to other treatments. The goal is to see if giving this therapy frequently can quickly improve their symptoms.

Eligible Conditions
  • Major Depressive Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at screening (within a week of starting treatment) to a week post treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and at screening (within a week of starting treatment) to a week post treatment for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Remission of depressive symptoms using the Hamilton Depression Rating Scale (HAM - D or HDRS) - 17 version
Secondary study objectives
Change in World Health Organization Disability assessment scale (WHODAS)
Change in the Quality of Life, Enjoyment, and Satisfaction Questionnaire (QUAL-ES-Q)
Improvement overall using the Clinical Global Severity/Impression Scale (CGI-I)
+3 more
Other study objectives
Adverse effects of the treatment

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Patients receiving accelerated rTMSExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Intermittent Theta Burst Stimulation (form of repetitive transcranial magnetic stimulation) given in an accelerated form
2022
N/A
~30

Find a Location

Who is running the clinical trial?

Ontario Shores Centre for Mental Health SciencesLead Sponsor
13 Previous Clinical Trials
2,111 Total Patients Enrolled
Robyn WaxmanPrincipal InvestigatorOntario Shores
~6 spots leftby Nov 2025
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