Time in Glucose Hospital Target
(TIGHT Trial)

Recruiting in Palo Alto (17 mi)

+5 other locations

Overseen byJudy Sibayan, MPH, CCRP

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Jaeb Center for Health Research

No Placebo Group

Trial Summary

What is the purpose of this trial?

This trial tests if using continuous monitoring of blood sugar levels can help hospitalized diabetes patients maintain better blood sugar levels without increasing the risk of low blood sugar. The study compares usual care with a new method that uses continuous monitoring of blood sugar levels. The goal is to see if the new method can improve patient outcomes, especially during infections like COVID-19. These monitoring systems have been shown to help manage blood sugar and improve safety in different healthcare settings.

Research Team

Irl Hirsch, MD

Principal Investigator

University of Washington

Judy Sibayan, MPH, CCRP

Principal Investigator

Jaeb Center for Health Research

Roy Beck, MD, PhD

Principal Investigator

Jaeb Center for Health Research

Eligibility Criteria

Inclusion Criteria

You are hospitalized on a non-ICU floor for a non-critical condition.

Type 2 diabetes (per investigator assessment); or if not previously diagnosed as having diabetes, HbA1c>=7.0% (laboratory-measured at or since hospital admission or within prior 3-months).

At least 1 blood glucose measurement >180 mg/dL since admission

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Exclusion Criteria

Diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemic state (HHS) in the 6 months prior to hospital admission, at hospital admission or prior to randomization during the current hospital admission

One or more severe hypoglycemic events within the 6 months prior to hospital admission or prior to randomization during the current admission

Blood glucose >400 mg/dL at time of potential enrollment (most recent blood glucose measurement in hospital)

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