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Local Anesthetic

Trial Comparing Transversus Abdominis Plane Block Versus Epidural Anesthesia for Pain Management in Colorectal Surgery (TAP Trial)

N/A
Waitlist Available
Led By Robert K Cleary, MD
Research Sponsored by Saint Joseph Mercy Health System
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up post-operative day 3
Awards & highlights
No Placebo-Only Group

Summary

The primary outcome for this study is the Numeric Pain Score (NPS) for elective patients undergoing elective colorectal surgery that have been randomized to transversus abdominis plane block or epidural anesthesia for the management of perioperative pain in elective colorectal surgery.

Eligible Conditions
  • Diverticulosis
  • Colon Cancer
  • Colorectal Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~post-operative day 3
This trial's timeline: 3 weeks for screening, Varies for treatment, and post-operative day 3 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Post-operative pain control day 1 using the numeric pain scale
Post-operative pain control day 2 using the numeric pain scale
Post-operative pain control day 3 using the numeric pain scale
Secondary study objectives
Overall benefits of analgesia treatment post-operative day 1
Overall benefits of analgesia treatment post-operative day 2
Overall benefits of analgesia treatment post-operative day 3
Other study objectives
Patient use of supplemental narcotic analgesia post-operative day 1
Patient use of supplemental narcotic analgesia post-operative day 2
Patient use of supplemental narcotic analgesia post-operative day 3

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Active Control
Group I: TAP Block- ExparelActive Control1 Intervention
Transversus abdominis plane block utilizing the medication Exparel®
Group II: Continuous Epidural AnalgesiaActive Control1 Intervention
Continuous Epidural Analgesia

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Who is running the clinical trial?

Saint Joseph Mercy Health SystemLead Sponsor
12 Previous Clinical Trials
6,105 Total Patients Enrolled
Robert K Cleary, MDPrincipal InvestigatorSaint Joseph Mercy Hospital
~19 spots leftby Dec 2025
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