Neural Computations for Decision-Making in Epilepsy

Recruiting in Palo Alto (17 mi)

Overseen byJohn O'Doherty, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Cedars-Sinai Medical Center

No Placebo Group

Trial Summary

What is the purpose of this trial?

The purpose of this research is to better understand how the human brain accomplishes the cognitive task of making goal-directed decisions. These investigations are critical to better understand human cognition and to design treatments for disorders of decision making and performance monitoring.

Eligibility Criteria

This trial is for individuals aged 13 or older with intractable epilepsy who are undergoing invasive monitoring. Participants must be able to understand and perform tasks using a computer response pad, and have an IQ over 70. Those unable to complete the tasks due to cognitive, psychological limits, or pain cannot join.

Inclusion Criteria

I am 13 years old or older.

I can understand and respond to simple tasks on a computer.

Full Scale Intelligence Quotient > 70

See 1 more

Exclusion Criteria

Determination by clinicians and investigators that a patient is unable to complete the behavioral tasks required for the protocol due to either cognitive limits, psychological limits, or pain

Treatment Details

Interventions

Adtech Behnke-Fried micro-electrodes (Procedure)
Cedrus RB-844 response pad (Behavioral Intervention)
Neurolynx electrophysiology system (Procedure)

Trial OverviewThe study tests how people with epilepsy make decisions by using a Cedrus RB-844 response pad, Adtech Behnke-Fried micro-electrodes, and Neurolynx electrophysiology system during goal-directed tasks.

Participant Groups

1Treatment groups

Experimental Treatment

Group I: Behavioral TestingExperimental Treatment1 Intervention

Behavioral and Neuronal Recordings