Look AHEAD: Action for Health in Diabetes

(LookAHEAD Trial)

Recruiting in Palo Alto (17 mi)

+17 other locations

Overseen by Mark A Espeland, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Wake Forest University Health Sciences

No Placebo Group

Approved in 2 Jurisdictions

Trial Summary

What is the purpose of this trial?

The Look AHEAD study is a multi-center, randomized clinical trial to examine the long-term effects of a lifestyle intervention designed to achieve and maintain weight loss. The study will investigate the effects of the intervention on heart attacks, stroke and cardiovascular-related death in individuals with type 2 diabetes who are also overweight or obese.

Research Team

Mark A Espeland, PhD

Principal Investigator

Wake Forest University Health Sciences

Eligibility Criteria

Inclusion Criteria

Type 2 diabetes

Overweight

BMI of 25 kg/m2 or greater

Treatment Details

Interventions

• Diabetes Support and Education (Behavioral Intervention)
• Lifestyle Intervention (Behavioral Intervention)

Participant Groups

Group I: Lifestyle Intervention Experimental Treatment 1 Intervention

Participants in the lifestyle intervention arm are offered individual and group sessions designed to help achieve and maintain weight loss.

Group II: Diabetes Support and Education Active Control 1 Intervention

The diabetes support and education arm provides group sessions on diabetes management and social support.

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

The Miriam Hospital Providence, RI

University of Minnesota Minneapolis, MN

University of Pennsylvania Medical Center Philadelphia, PA

University of Pittsburgh Pittsburgh, PA

More Trial Locations

Who Is Running the Clinical Trial?

Wake Forest University Health Sciences

Lead Sponsor

Trials

1432

Patients Recruited

2,506,000+

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborator

Trials

2513

Patients Recruited

4,366,000+

Office of Research on Women's Health (ORWH)

Collaborator

Trials

34

Patients Recruited

36,300+

Centers for Disease Control and Prevention

Collaborator

Trials

902

Patients Recruited

25,020,000+

National Heart, Lung, and Blood Institute (NHLBI)

Collaborator

Trials

3987

Patients Recruited

47,860,000+

National Institute of Nursing Research (NINR)

Collaborator

Trials

623

Patients Recruited

10,400,000+

National Institute on Minority Health and Health Disparities (NIMHD)

Collaborator

Trials

473

Patients Recruited

1,374,000+