114 Participants Needed

Echocardiography Techniques for Heart Surgery

(CM-TTE-TEE Trial)

JM
LK
Overseen ByLilia Kaustov, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Sunnybrook Health Sciences Centre
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial compares two ultrasound techniques used during heart surgery to evaluate their effectiveness in assessing heart chamber sizes. The two methods are transthoracic echocardiography (TTE), where an ultrasound probe is placed on the chest, and transesophageal echocardiography (TEE), where a probe is inserted into the esophagus for closer images. The trial aims to determine how these techniques agree under anesthesia and how factors like breathing affect measurements. It seeks adult patients scheduled for heart surgery who have normal heart function and require ultrasound checks during surgery. Participants will undergo TTE before and after surgery and TEE during surgery, which are standard procedures.

As an unphased trial, this study provides patients the opportunity to contribute to research that may enhance heart surgery outcomes.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that these ultrasound techniques are safe for heart surgery patients?

Research has shown that both transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) are safe and commonly used during heart surgeries. TEE enhances surgical results and reduces the risk of death in patients undergoing high-risk heart surgeries by providing clear images of the heart, aiding doctors in making better decisions during surgery.

TTE involves placing an ultrasound device on the chest. It is non-invasive and a standard part of heart surgery care. Both TEE and TTE have been used safely for many years and are crucial for helping doctors understand heart conditions during surgery.

Overall, these imaging techniques are well-tolerated, with no major safety concerns reported in studies. They are considered routine and safe parts of heart surgery procedures.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it compares two different ways of measuring heart chambers during cardiac surgery. Typically, transthoracic echocardiography (TTE) is used for heart imaging, but in this trial, they're also looking at transesophageal echocardiography (TEE) under anesthesia. TEE offers a closer and potentially clearer view of the heart since it's done through the esophagus, which could lead to more accurate measurements during surgery. By directly comparing TTE and TEE, the trial aims to find out if TEE provides better information for guiding surgical decisions, which could improve outcomes for patients undergoing heart surgery.

What evidence suggests that these ultrasound techniques are effective for evaluating heart chamber dimensions during surgery?

This trial will compare transesophageal echocardiography (TEE) and transthoracic echocardiography (TTE) in cardiac surgery patients. Studies have shown that TEE during heart surgery greatly aids doctors in making better decisions and is linked to improved patient outcomes, such as a lower risk of death. Research indicates that TEE provides clearer and closer images of the heart, which can be crucial during surgery. In contrast, TTE is a non-invasive method where the ultrasound device is placed on the chest. TTE remains effective and can predict changes in heart function and blood pressure. Both techniques are valuable, but TEE might offer more detailed information during surgery.12346

Who Is on the Research Team?

JM

Jacobo Moreno Garijo, MD, PhD

Principal Investigator

Sunnybrook Health Science Centre

Are You a Good Fit for This Trial?

Inclusion Criteria

I am 18 or older and can give my consent.
I am scheduled for heart surgery that involves improving blood flow to the heart.
I need a heart ultrasound during surgery.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2 weeks

Preoperative Assessment

Participants undergo preoperative transthoracic echocardiography (TTE) to measure cardiac chamber dimensions

Within 2 weeks prior to surgery
1 visit (in-person)

Intraoperative Assessment

Participants undergo intraoperative transesophageal echocardiography (TEE) during surgery to measure cardiac chamber dimensions

During surgery
1 visit (in-person)

Follow-up

Participants are monitored for any discrepancies in cardiac measurements and the impact of anesthesia and PEEP

2 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Transesophageal Echocardiography (TEE)
  • Transthoracic Echocardiography (TTE)

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Cardiac Surgery PatientsExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Sunnybrook Health Sciences Centre

Lead Sponsor

Trials
693
Recruited
1,569,000+

Citations

Surgical Volume and Outcomes of Intraoperative ... - PMC - NIH

Transesophageal echocardiography (TEE) is used during cardiac surgery to guide intraoperative decisions and is associated with improved outcomes ...

Surgical Volume and Outcomes of Intraoperative ...

Transesophageal echocardiography (TEE) is used during cardiac surgery to guide intraoperative decisions and is associated with improved outcomes ...

Considerations of Intraoperative Transesophageal ...

TEE use is associated with reduced mortality, improved outcomes, and improved surgical decision-making in cardiac surgery. Bottom icons ...

Considerations of Intraoperative Transesophageal ...

Intraoperative TEE use has been shown to improve outcomes and reduce mortality in high-risk cardiac surgery patients, particularly those ...

Association between Transesophageal Echocardiography ...

The findings from this study suggest that TEE may offer a clinical benefit to cardiac surgical patients undergoing isolated CABG surgery.

Association between Transesophageal Echocardiography ...

The findings from this study suggest that TEE may offer a clinical benefit to cardiac surgical patients undergoing isolated CABG surgery.