Magnetocardiography for Chest Pain
(MCG Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if a new method called magnetocardiography (MCG) can quickly and accurately diagnose chest pain caused by coronary ischemia, which means reduced blood flow to the heart. The researchers seek to establish whether MCG outperforms the usual tests in the emergency department for identifying heart-related chest pain. Individuals who arrive at the emergency room with sudden chest pain, suspected of having heart issues, but show unclear results on standard tests, might be suitable for this trial. As a Phase 2 trial, this research measures how well MCG works in an initial, smaller group of people, offering participants a chance to contribute to important advancements in heart diagnostics.
Do I have to stop taking my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that magnetocardiography (MCG) is safe for diagnosing chest pain?
Research has shown that magnetocardiography (MCG) provides a safe and easy method for detecting heart problems. MCG is non-invasive, requiring no cuts or needles. It also avoids radiation exposure and does not use special dyes, unlike some other tests. Studies have found no specific side effects associated with MCG. Specifically, one study found no negative reactions, highlighting its usefulness for doctors in emergencies. Overall, MCG offers a low-risk option for diagnosing heart-related chest pain.12345
Why are researchers excited about this trial?
Researchers are excited about this trial because magnetocardiography (MCG) offers a new way to diagnose heart issues, specifically ischemia, in patients with chest pain at the emergency department. Unlike traditional methods like electrocardiograms (ECGs) or stress tests, which can be less sensitive to some types of heart problems, MCG uses magnetic fields to capture heart activity, potentially providing a more accurate picture. This can lead to quicker and more precise diagnoses, which is crucial in emergency settings where time is of the essence.
What evidence suggests that magnetocardiography (MCG) is effective for diagnosing coronary ischemia in patients with chest pain?
Research has shown that magnetocardiography (MCG) can help diagnose coronary ischemia, a condition where the heart doesn't receive enough blood. Studies have found that MCG outperforms standard electrocardiograms (ECGs) for this purpose. Specifically, one study found that MCG correctly identified ischemia in many cases, with a sensitivity of 66.7%. Another study demonstrated that MCG's accuracy improves with advanced data analysis. Overall, MCG has shown promising results as a non-invasive method to detect coronary ischemia in patients with chest pain.16789
Who Is on the Research Team?
Sara Hevesi, MD
Principal Investigator
Mayo Clinic
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Diagnostic Assessment
Participants undergo magnetocardiography (MCG) to assess the accuracy of diagnosing acute coronary syndrome (ACS) in real-time
Follow-up
Participants are monitored for major adverse cardiac events (MACE) at 3 days, 7 days, 30 days, and 90 days
What Are the Treatments Tested in This Trial?
Interventions
- Magnetocardiography (MCG)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Mayo Clinic
Lead Sponsor
Citations
Diagnostic outcomes of magnetocardiography in patients ...
Conclusions: Our result showed that resting MCG under condition of an advanced data analysis has higher diagnostic outcomes and is superior to ECG or ...
Magnetoionography enhances diagnostic accuracy of ...
This study evaluates the efficacy of magnetoionography (MIG), a novel parameter extension of magnetocardiography (MCG), in improving the ...
3.
frontiersin.org
frontiersin.org/journals/medical-technology/articles/10.3389/fmedt.2025.1611046/fullEffectiveness of magnetocardiography as a non-invasive ...
Magnetocardiography (MCG) demonstrated comparably high diagnostic efficiency for detecting coronary ischemia in previous studies. However, limited evidence ...
Accelerated magnetocardiography in the evaluation of ...
3.1. Efficacy of magnetocardiography compared to SOC non-invasive stress testing. The sensitivity and specificity of MCG was 66.7 % (95 % CI 50.5 %–80.5 %) and ...
Application of Magnetocardiography to Screen for ...
The magnetocardiography vector decreased from 0.10 at baseline to 0.07 within 7 days (P=0.010) and to 0.03 within 30 days (P<0.001). After 30 ...
Magnetocardiography for the detection of myocardial ...
Magnetocardiography (MCG) is a non-contact, non-invasive method that records magnetic fields produced by the electrical activity of the heart.
National cost savings, operational and safety benefits from ...
Magnetocardiography (MCG) is a rapid, low-risk, cost-effective test that can save $574 million annually by avoiding 555,000 downstream tests, and reduce ...
Magnetocardiography as a Tool for Patients Presenting ...
The aim of this pilot study is to identify characteristics of MCG that differentiate patients with non-ischaemic chest pain from those with a myocardial ...
Abstract 4140246: AI and Quantum Sensors
No adverse events were reported. Conclusions: MCG is a promising, non-contact diagnostic tool for emergency physicians diagnosing suspected ACS ...
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