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Brain Stimulation for Emotions

N/A
Waitlist Available
Led By Edward F Chang, MD
Research Sponsored by University of California, San Francisco
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during inpatient hospitalization, approximately 4-14 days
Awards & highlights

Study Summary

This trial will test how well recording brain activity can help map out emotions and how different brain networks may be linked to psychiatric symptoms.

Who is the study for?
This trial is for individuals with epilepsy at UCSF who are undergoing surgical electrode implantation and can cooperate with study tasks. It's not suitable for those unable to consent, with significant brain lesions, or cognitive deficits that prevent reliable task completion.Check my eligibility
What is being tested?
The study investigates how the emotion network in the brain operates by having participants view visual stimuli and receive electrical stimulation. The aim is to understand emotional behavior changes and affective symptoms like depression and anxiety.See study design
What are the potential side effects?
Since this research involves observation of neural activity rather than drug testing, traditional side effects aren't a concern. However, there may be risks associated with discomfort from viewing stimuli or potential stress during electrical brain stimulation.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during inpatient hospitalization, approximately 4-14 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and during inpatient hospitalization, approximately 4-14 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Mean Change from Baseline in Heart Rate
Mean Change from Baseline in Neural Activity within the Emotion Network
Mean Change from Baseline in Respiratory Rate
+2 more
Secondary outcome measures
Mean Subjective Experience

Trial Design

1Treatment groups
Experimental Treatment
Group I: Video and stimulation-based induction of emotionExperimental Treatment1 Intervention
Participants viewed visual stimuli while undergoing stimulation of brain regions involved in emotion during their inpatient hospitalization at the University of California, San Francisco (UCSF).

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Who is running the clinical trial?

University of California, San FranciscoLead Sponsor
2,519 Previous Clinical Trials
15,241,723 Total Patients Enrolled
1 Trials studying Emotions
40 Patients Enrolled for Emotions
San Francisco State UniversityOTHER
11 Previous Clinical Trials
2,357 Total Patients Enrolled
National Institute of Mental Health (NIMH)NIH
2,798 Previous Clinical Trials
2,660,818 Total Patients Enrolled
5 Trials studying Emotions
1,381 Patients Enrolled for Emotions

Media Library

Viewing visual stimuli and electrical stimulation of the brain Clinical Trial Eligibility Overview. Trial Name: NCT05152992 — N/A
Emotions Research Study Groups: Video and stimulation-based induction of emotion
Emotions Clinical Trial 2023: Viewing visual stimuli and electrical stimulation of the brain Highlights & Side Effects. Trial Name: NCT05152992 — N/A
Viewing visual stimuli and electrical stimulation of the brain 2023 Treatment Timeline for Medical Study. Trial Name: NCT05152992 — N/A
~28 spots leftby Jun 2026
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