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Brain Stimulation for Emotions

N/A

Waitlist Available

Led By Virginia Sturm, PhD

Research Sponsored by University of California, San Francisco

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Must not have

Participants with cognitive deficits that preclude reliable completion of study tasks.

Participants who lack capacity or decline to provide informed consent

Timeline

Screening 3 weeks

Treatment Varies

Follow Up during inpatient hospitalization, approximately 4-14 days

Awards & highlights

No Placebo-Only Group

Summary

This trial will test how well recording brain activity can help map out emotions and how different brain networks may be linked to psychiatric symptoms.

Who is the study for?

This trial is for individuals with epilepsy at UCSF who are undergoing surgical electrode implantation and can cooperate with study tasks. It's not suitable for those unable to consent, with significant brain lesions, or cognitive deficits that prevent reliable task completion.

What is being tested?

The study investigates how the emotion network in the brain operates by having participants view visual stimuli and receive electrical stimulation. The aim is to understand emotional behavior changes and affective symptoms like depression and anxiety.

What are the potential side effects?

Since this research involves observation of neural activity rather than drug testing, traditional side effects aren't a concern. However, there may be risks associated with discomfort from viewing stimuli or potential stress during electrical brain stimulation.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I am able to understand and complete study tasks.

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I am unable or unwilling to give consent for this trial.

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I have significant brain lesions.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ during inpatient hospitalization, approximately 4-14 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~during inpatient hospitalization, approximately 4-14 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and during inpatient hospitalization, approximately 4-14 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Mean Change from Baseline in Heart Rate

Mean Change from Baseline in Neural Activity within the Emotion Network

Mean Change from Baseline in Respiratory Rate

+2 more

Secondary study objectives

Mean Subjective Experience

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Video and stimulation-based induction of emotionExperimental Treatment1 Intervention

Participants viewed visual stimuli while undergoing stimulation of brain regions involved in emotion during their inpatient hospitalization at the University of California, San Francisco (UCSF).

0 / 3Eligibility criteria met