Re-irradiation for Breast Cancer
(BRASIL Trial)

Recruiting in Palo Alto (17 mi)

+1 other location

Overseen byYoussef Zeidan, M.D., Ph.D.

Age: 18+

Sex: Female

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Baptist Health South Florida

No Placebo Group

Trial Summary

What is the purpose of this trial?The purpose of this research study is to test the safety and possible harms of treating breast cancer with reirradiation, after breast surgery. The researchers want to find out what effects (good and bad) reirradiation has on people who have already received radiation before surgery.

Eligibility Criteria

This trial is for individuals who have had breast cancer and are undergoing a second lumpectomy. It's specifically for those who've already received radiation therapy before surgery and are now considering reirradiation.

Inclusion Criteria

Stated willingness to comply with all study procedures and availability for the duration of the study

I am 40 years old or older.

My breast cancer is ER positive and HER2 negative.

+9 more

Exclusion Criteria

My cancer affects my skin.

I have no other cancers except possibly skin cancer.

Pregnancy or breastfeeding

+6 more

Participant Groups

The study is examining the safety of Intensity Modulated Radiation Therapy (IMRT) as a form of reirradiation in patients who have previously undergone radiation treatment for breast cancer following their second lumpectomy.

1Treatment groups

Experimental Treatment

Group I: Partial Breast Irradiation (PBI)Experimental Treatment1 Intervention