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Analgesic

The Effects of Acetaminophen on Fear

N/A
Waitlist Available
Led By Pat Barclay, Ph.D.
Research Sponsored by University of Guelph
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 hour after taking acetaminophen or placebo
Awards & highlights
All Individual Drugs Already Approved
Approved for 10 Other Conditions

Summary

This trial investigates whether acetaminophen can reduce fear responses in people. It aims to see if the drug can help those with anxiety by making them feel less scared, similar to how it reduces other types of pain.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 hour after taking acetaminophen or placebo
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 hour after taking acetaminophen or placebo for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Decision on whether to do the plank walk again with virtual spiders
Distance walked on plank
Heart rate
+4 more
Secondary study objectives
Speed towards virtual elevator after turning around on plank
Time before needing a break or quitting the virtual reality plank walk
Time to take first step onto plank

Awards & Highlights

All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Approved for 10 Other Conditions
This treatment demonstrated efficacy for 10 other conditions.

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Acetaminophen ConditionExperimental Treatment1 Intervention
1000 mg acetaminophen
Group II: Placebo ConditionPlacebo Group1 Intervention
1000 mg microcrystalline cellulose
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Acetaminophen
FDA approved

Find a Location

Who is running the clinical trial?

University of GuelphLead Sponsor
84 Previous Clinical Trials
14,763 Total Patients Enrolled
1 Trials studying Anxiety
200 Patients Enrolled for Anxiety
Natural Sciences and Engineering Research Council, CanadaOTHER
62 Previous Clinical Trials
3,016 Total Patients Enrolled
1 Trials studying Anxiety
60 Patients Enrolled for Anxiety
Pat Barclay, Ph.D.Principal InvestigatorUniversity of Guelph
~73 spots leftby Dec 2025
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