160 Participants Needed

Imaging Techniques for Glaucoma

(FSOCT Trial)

DR
CD
Overseen ByChinmay Deshpande, M.Optom.
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Oregon Health and Science University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to develop and test advanced imaging tools for early glaucoma detection. Researchers are creating new methods to examine the eye's structure and blood flow using special imaging techniques. The trial seeks to predict how glaucoma might begin or progress over time. Individuals with normal eye health or early signs of glaucoma, such as optic nerve changes or visual field issues, may be suitable for this study. As an unphased trial, it offers participants the chance to contribute to groundbreaking research that could lead to earlier detection and improved management of glaucoma.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but you cannot participate if you use chronic ocular or systemic corticosteroids.

Why are researchers excited about this trial?

Researchers are excited about the trial on functional and structural imaging for glaucoma because it could revolutionize how we diagnose and monitor this eye condition. Unlike current treatments that focus on lowering eye pressure through medications or surgery, this approach aims to enhance our understanding of glaucoma by providing detailed images of the eye's structure and function. This could lead to earlier detection and more personalized treatment plans, potentially improving outcomes for patients.

Who Is on the Research Team?

AC

Aiyin Chen, MD

Principal Investigator

Oregon Health and Science University

Are You a Good Fit for This Trial?

Inclusion Criteria

Open angle (gonioscopy must show 75% or more of the angle to be Grade 2 or more by Shaffer's grading system)
Inclusion Criteria: Normal Subjects (both eyes must meet all criteria)
No history or evidence of retinal pathology or glaucoma
See 7 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Imaging Development

Development and validation of high-resolution OCT and OCT angiography prototypes to improve imaging of structure and perfusion

12 months

Data Collection and Analysis

Collection of data using developed OCT methods to simulate visual field results and assess glaucoma detection, conversion, and progression

12 months

Follow-up

Participants are monitored for safety and effectiveness after imaging and data collection

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • None

Find a Clinic Near You

Who Is Running the Clinical Trial?

Oregon Health and Science University

Lead Sponsor

Trials
1,024
Recruited
7,420,000+

National Eye Institute (NEI)

Collaborator

Trials
572
Recruited
1,320,000+
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