Your session is about to expire
← Back to Search
Functional MRI for Brain Tumor Surgery Assessment
N/A
Recruiting
Led By Ho-Ling A Liu
Research Sponsored by M.D. Anderson Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 6 weeks
Awards & highlights
Study Summary
This trial looks at how well two types of MRI work in measuring language function before and after surgery for brain tumors.
Who is the study for?
This trial is for right-handed English speakers with a new brain mass suspected to be glioma, located near critical language areas. They must not have had prior neurologic diseases or treatments affecting cognition and should agree to pre- and post-surgery neuropsychological tests.Check my eligibility
What is being tested?
The study measures the impact of surgery on language functions in glioma patients using resting-state functional MRI and cerebrovascular reactivity MRI before and after their operations.See study design
What are the potential side effects?
Since this trial involves non-invasive imaging techniques like MRI, side effects are minimal but may include discomfort from lying still during the scan or noise from the machine.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 6 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 6 weeks
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Detectability of language networks
Secondary outcome measures
Changes in resting-state functional connectivity and neuropsychological outcomes
Trial Design
1Treatment groups
Experimental Treatment
Group I: Diagnostic (fMRI, CVR MRI, rs-fMRI)Experimental Treatment3 Interventions
Patients undergo standard of care fMRI, CVR MRI over 3 minutes, and rs-fMRI over 6 minutes 1 month before and within 6 weeks after standard of care surgery.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Functional Magnetic Resonance Imaging
2016
Completed Phase 4
~890
Magnetic Resonance Imaging
2017
Completed Phase 3
~1160
Find a Location
Who is running the clinical trial?
M.D. Anderson Cancer CenterLead Sponsor
2,992 Previous Clinical Trials
1,792,625 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,721 Previous Clinical Trials
40,965,028 Total Patients Enrolled
Ho-Ling A LiuPrincipal InvestigatorM.D. Anderson Cancer Center
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You have received radiation therapy or chemotherapy in the past.You are right-handed.The tumor is in an area of your brain that is important for language.
Research Study Groups:
This trial has the following groups:- Group 1: Diagnostic (fMRI, CVR MRI, rs-fMRI)
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger