Meals with Potatoes + Protein for Blood Sugar Control
Recruiting in Palo Alto (17 mi)
Overseen ByG. Harvey Anderson, PhD
Age: 18 - 65
Sex: Any
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: Academic
Recruiting
Sponsor: University of Toronto
No Placebo Group
Trial Summary
What is the purpose of this trial?The proposed study aims to simulate a meal eaten at home, where meals will provide a fixed amount of protein from beef or vegetarian substitute "meat" balls with ad libitum access to one of mashed potatoes, full-fat fries, or pasta. Postprandial glycemia (PPG), insulin, active ghrelin, satiety, amino acid response and food intake (FI) at the meal and again 3h later (after an ad libitum pizza meal) will be measured. In addition, post-meal PPG and satiety will be measured for one hour after the second meal.
Eligibility Criteria
This trial is for adults aged 18-45 with a BMI between 18.5 and 24.9, who are willing to maintain their usual diet, exercise, and weight. They must not smoke or have certain health conditions like thyroid issues or gastrointestinal disorders, can't be pregnant or lactating, and should not consume alcohol or marijuana during the study.Participant Groups
The study tests how different meals with potatoes or pasta combined with beef meatballs or vegetarian substitutes affect blood sugar control and feelings of fullness. Participants will eat these meals freely at one sitting and then have pizza three hours later while researchers measure various responses.
6Treatment groups
Experimental Treatment
Group I: Ad libitum macaroni pasta with vegetarian substitute meatballsExperimental Treatment1 Intervention
Ad libitum carbohydrate side with fixed amount of protein: Ad libitum macaroni pasta with vegetarian substitute meatballs (25 g protein)
Group II: Ad libitum macaroni pasta with beef meatballsExperimental Treatment1 Intervention
Ad libitum carbohydrate side with fixed amount of protein: Ad libitum macaroni pasta with beef meatballs (25 g protein)
Group III: Ad libitum instant mashed potatoes with vegetarian substitute meatballsExperimental Treatment1 Intervention
Ad libitum carbohydrate side with fixed amount of protein: Ad libitum instant mashed potatoes with vegetarian substitute meatballs (25 g protein)
Group IV: Ad libitum instant mashed potatoes with beef meatballsExperimental Treatment1 Intervention
Ad libitum carbohydrate side with fixed amount of protein: Ad libitum instant mashed potatoes with beef meatballs (25 g protein)
Group V: Ad libitum full-fat French fries with vegetarian substitute meatballsExperimental Treatment1 Intervention
Ad libitum carbohydrate side with fixed amount of protein: Ad libitum full-fat French fries with vegetarian substitute meatballs (25 g protein)
Group VI: Ad libitum full-fat French fries with beef meatballsExperimental Treatment1 Intervention
Ad libitum carbohydrate side with fixed amount of protein: Ad libitum full-fat French fries with beef meatballs (25 g protein)
Find A Clinic Near You
Research locations nearbySelect from list below to view details:
University of Toronto - Department of Nutritional SciencesToronto, Canada
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Who is running the clinical trial?
University of TorontoLead Sponsor
Alliance for Potato Research and EducationCollaborator