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Skin Patch Monitor for Gout

N/A

Waitlist Available

Led By John FitzGerald, MD

Research Sponsored by University of California, Los Angeles

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age > 18 with diagnosis of gout (screening positive ACR/EULAR Gout Classification Criteria - see screening survey) and eGFR > 60 (within the last 12-months)

Be older than 18 years old

Must not have

Contraindications to miosis, which include acute iritis, narrow-angle glaucoma

Pupillary block glaucoma (ophthalmic solution)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 years

Awards & highlights

No Placebo-Only Group

Summary

This trial will invite 15 patients with gout to participate in a meal at UCLA and a 7-day follow-up. They will use a skin patch to measure uric acid levels and other substances

Who is the study for?

This trial is for 15 people with gout, some of whom haven't had recent urate-lowering therapy and others who are on a stable urate-lowering regimen. Participants will join a meal study at UCLA and then wear a skin patch that monitors uric acid levels for a week.

What is being tested?

The UR+AIMS skin patch, which tracks uric acid and other metabolites in patients with gout, is being tested. The study involves eating a standardized meal followed by wearing the patch to monitor changes over seven days.

What are the potential side effects?

Potential side effects aren't specified but may include skin irritation or allergic reactions where the patch is applied. As this device monitors levels without administering drugs, systemic side effects are unlikely.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am over 18, have gout, and my kidney function is good.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I do not have conditions like acute iritis or narrow-angle glaucoma.

Select...

I have been diagnosed with pupillary block glaucoma.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Evaluate tolerability and adherence of daily recorded patch wear time.

Recording of uric acid (and oxypurinol) measurements while wearing patch.

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Uric Acid and Metabolite Monitor System (UR+AIMS) skin patchExperimental Treatment1 Intervention

15 patients with gout will be invited to participate in a standardized meal at the UCLA Human Nutrition Center and a 7-day community follow up for the measurement of uric acid (and other metabolites) using our Uric Acid and Metabolite Monitor System (UR+AIMS) skin patch.

0 / 3Eligibility criteria met