Skin Patch Monitor for Gout

Recruiting in Palo Alto (17 mi)

Overseen byJohn FitzGerald, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of California, Los Angeles

No Placebo Group

Trial Summary

What is the purpose of this trial?15 patients with gout \[10 patients no recent urate-lowering therapy (ULT) and 5 patients on stable urate-lowering therapy (ULT)\] will be invited to participate in a standardized meal at the UCLA Human Nutrition Center and a 7-day community follow-up for the measurement of uric acid (and other metabolites) using our Uric Acid and Metabolite Monitor System (UR+AIMS) skin patch.

Eligibility Criteria

This trial is for 15 people with gout, some of whom haven't had recent urate-lowering therapy and others who are on a stable urate-lowering regimen. Participants will join a meal study at UCLA and then wear a skin patch that monitors uric acid levels for a week.

Inclusion Criteria

I am over 18, have gout, and my kidney function is good.

I have gout, haven't taken gout medication in the last 6 months, and my uric acid level is above 7 mg/dL.

I have gout and have been on a stable dose of urate-lowering therapy for the last 30 days.

Exclusion Criteria

I do not have conditions like acute iritis or narrow-angle glaucoma.

Known Hypersensitivity to pilocarpine hydrochloride

I have been diagnosed with pupillary block glaucoma.

+1 more

Participant Groups

The UR+AIMS skin patch, which tracks uric acid and other metabolites in patients with gout, is being tested. The study involves eating a standardized meal followed by wearing the patch to monitor changes over seven days.

1Treatment groups

Experimental Treatment

Group I: Uric Acid and Metabolite Monitor System (UR+AIMS) skin patchExperimental Treatment1 Intervention

15 patients with gout will be invited to participate in a standardized meal at the UCLA Human Nutrition Center and a 7-day community follow up for the measurement of uric acid (and other metabolites) using our Uric Acid and Metabolite Monitor System (UR+AIMS) skin patch.