Stroke > Validation Of Early Prognostic Data

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

(VERIFY Trial)

Recruiting in Palo Alto (17 mi)

+32 other locations

Overseen By Steve Cramer, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Recruiting

Sponsor: University of Cincinnati

No Placebo Group

Approved in 2 jurisdictions

Trial Summary

What is the purpose of this trial?

VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, large-scale, prospective dataset of clinical, transmagnetic stimulation (TMS), and MRI measures in the acute stroke time window.

Eligibility Criteria

Inclusion Criteria

Age 18 years or older

Unilateral stroke due to ischemia or intracerebral hemorrhage

Motor deficits in the acutely affected UE, defined as a Shoulder Abduction and Finger Extension (SAFE) score ≤ 8 out of 10 points (i.e., excluding full or nearly full motor strength in both shoulder abduction and finger extension) within 48 to 96 hours of stroke onset (or time last known well).

Participant Groups

Group I: Ischemic & Hemorrhagic stroke patients Experimental Treatment 1 Intervention

557 ischemic stroke patients and 100 hemorrhagic stroke patients

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

UT Southwestern Medical Center Dallas, TX

Baystate Medical Center Springfield, MA

University of Michigan Ann Arbor, MI

Pennsylvania Hospital Philadelphia, PA

More Trial Locations

Who Is Running the Clinical Trial?

University of Cincinnati Lead Sponsor

University of California, Los Angeles Collaborator

University of Auckland, New Zealand Collaborator

Medical University of South Carolina Collaborator

References