What side effects are associated with this type of intervention?

The most common treatment for Hoarding Disorder is cognitive-behavioral therapy (CBT), which generally has minimal side effects. Patients may experience temporary increases in anxiety or distress as they confront their hoarding behaviors and work through challenging thought patterns. Pharmacotherapy, often involving selective serotonin reuptake inhibitors (SSRIs), can be used as an adjunct to CBT. Common side effects of SSRIs include nausea, headache, sleep disturbances, and sexual dysfunction. It is important for patients to discuss potential side effects with their healthcare provider to manage and mitigate any adverse effects effectively.

What prior FDA approvals exist?

As of now, there are no specific FDA-approved medications for Hoarding Disorder. However, treatments often involve behavioral interventions similar to those used for OCD, such as Cognitive Behavioral Therapy (CBT). Medications like selective serotonin reuptake inhibitors (SSRIs), which are approved for OCD, may also be used off-label to help manage symptoms of Hoarding Disorder. The trial mentioned focuses on behavioral interventions, which align with the current best practices for treating this condition.

What other types of research exist?

Promising novel alternatives to behavioral interventions for hoarding disorder patients include pharmacological treatments such as selective serotonin reuptake inhibitors (SSRIs) and other medications that target underlying neurobiological mechanisms. Additionally, digital and internet-based cognitive-behavioral therapy (CBT) platforms, as well as smartphone-assisted self-help programs, have shown potential in recent studies. These alternatives offer accessible and scalable options for patients who may face barriers to traditional face-to-face therapy.

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Motivational Interviewing for Hoarding Disorder

N/A

Recruiting

Research Sponsored by Mississippi State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Have a primary psychiatric diagnosis of hoarding disorder

Aged 60+

Must not have

Concurrent psychotherapy focused on hoarding

Timeline

Screening 3 weeks

Treatment Varies

Follow Up four months

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing two methods to help older adults with hoarding disorder. One method combines motivational talks with sorting practice, while the other uses sorting practice alone. The goal is to see if motivational talks can make people more willing to clean up their homes.

Who is the study for?

This trial is for older adults aged 60 and above who have been diagnosed with hoarding disorder. Participants must live within a 60-minute drive of Starkville, MS. They should not be in another hoarding-focused therapy, have major cognitive issues, active psychosis or drug problems, or recent changes in their psychotropic medications.

What is being tested?

The study is comparing two behavioral treatments designed to help with hoarding disorder: 'RECLAIM' which aims to reduce clutter and increase life meaning, and 'Sorting Practice' that focuses on organizing items. The goal is to see which method works better for these individuals.

What are the potential side effects?

Since the interventions are behavioral therapies rather than medications, traditional side effects like those seen with drugs are not expected. However, participants may experience emotional discomfort or anxiety when confronting their hoarding behaviors during the sessions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have been diagnosed with hoarding disorder.

Select...

I am 60 years old or older.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I am currently receiving therapy for hoarding.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ four months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~four months

This trial's timeline: 3 weeks for screening, Varies for treatment, and four months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in duration of sorting/discarding behavior

Change in frequency of sorting/discarding behavior

Change in score on the Apathy Evaluation Scale (AES-S; Marin, 1991)

+1 more

Secondary study objectives

Rating on the Treatment Acceptability/ Adherence Scale (TAAS; Milsevic et al., 2015)

Other study objectives

Change in score on the Clutter Image Rating (CIR; Frost et al., 2008)

Change in score on the Saving Inventory-Revised (SI-R; Frost et al., 2004)

Change in scores on the Behavioral Approach Task for sorting/discarding(BAT; Dozier & Ayers, 2017; Dozier et al., 2020)

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: RECLAIM: Reducing Clutter and Increasing MeaningExperimental Treatment1 Intervention

Participants will receive a combination of motivational interviewing and sorting practice to reduce hoarding symptoms.

Group II: Sorting PracticeActive Control1 Intervention

Participants will receive sorting practice only to reduce hoarding symptoms.

0 / 3Eligibility criteria met

Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.

Mechanism Of Action

Side Effect Profile

Prior Approvals

Other Research

Cognitive Behavioral Therapy (CBT) is the most common treatment for Hoarding Disorder, focusing on modifying behavior and thought patterns. CBT helps patients identify and challenge distorted beliefs about possessions, reduce excessive acquiring, and improve decision-making skills. Exposure therapy, a component of CBT, involves gradual exposure to discarding items, which helps reduce anxiety associated with letting go of possessions. These mechanisms are crucial for Hoarding Disorder patients as they address the underlying cognitive and emotional factors contributing to hoarding behaviors, leading to more sustainable and effective management of the disorder.

Hoarding Disorder and a Systematic Review of Treatment with Cognitive Behavioral Therapy.