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Allulose sweetened commercial foods (processed and low added sugar) for High Blood Sugar

N/A

Waitlist Available

Research Sponsored by University of California, Irvine

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up each 14-day period

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing foods sweetened with allulose, a zero-calorie sugar, on people with prediabetes, diabetes, or high metabolic risk. The goal is to see if replacing regular sugar with allulose can reduce overall sugar intake and improve blood sugar levels. D-allulose is a non-calorie rare monosaccharide with 70% sweetness of sucrose, which has shown anti-diabetes effects in Asian populations.

Eligible Conditions

High Blood Sugar
High Blood Pressure
Eating Habits

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ each 14-day period

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~each 14-day period

This trial's timeline: 3 weeks for screening, Varies for treatment, and each 14-day period for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Glycemic Variability (and specifically the Coefficient of Variation -CV)

Secondary study objectives

Blood pressure

CGM Mean glucose

CGM Time in Range

+6 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups

Experimental Treatment

Group I: Whole and minimally processed and sweetened foods (low processed and low added sugar)Experimental Treatment1 Intervention

This period emphasizes incorporating minimally processed (e.g., intact whole grains) foods with minimal to no added sugar, aligning added sugar intake levels with recommendations from the American Heart Association and Dietary guidelines. Consume at least 1 daily serving of the chosen, minimal to no sweetened breakfast food in place of "usual" sweetened breakfast cereal/cereal-granola bar and consume a whole piece of fruit (or serving of fruit) in place of a sweetened baked goods/candy/desserts (at least 1 daily serving). * If they eat peanuts or nuts, consume plain or dry-roasted (no to low sodium) nuts/peanuts at least 3 days a week (1 serving), or as frequently as usual habits if more often * If consume sweetened beverages (artificial or regular) or sweetened coffee or tea, consume unsweetened coffee or tea and consume plain water in place of the sweetened beverages at the same frequency/amount that usually do

Group II: Regular sweetened commercial foods (processed and high added sugar)Experimental Treatment1 Intervention

This is the "usual" habits period. Participants consume the chosen, sweetened commercial products of their choice in the breakfast cereal/cereal-granola bar category (at least 1 daily serving) and sweetened baked goods/candy/desserts (at least 1 daily serving). * If they eat peanuts or nuts, and willingly consume chocolate covered peanuts or nuts, they will eat regular sweetened chocolate covered nuts/peanuts at least 3 days a week (1 serving/day), or as frequently as their usual habits if more often. * If they consume sweetened beverages (artificial or regular) or sweetened coffee or tea, they will consume these regular sweetened beverages as they usually do.

Group III: Allulose sweetened commercial foods (processed and low added sugar)Experimental Treatment1 Intervention

This period emphasizes minimizing added sugar, aligning intake levels with recommendations from the AHA and Dietary guidelines by consuming allulose sweetened products. Participants will eat at least 1 daily serving of the chosen, provided allulose sweetened breakfast/cereal-granola bar, and at least 1 daily serving of allulose sweetened baked goods/candy/desserts in place of the usual sweetened products from these food categories. * If they eat peanuts or nuts, and willingly consume chocolate covered peanuts or nuts, eat allulose sweetened chocolate covered nuts/peanuts at least 3 days a week (1 serving/day), or as frequently as usual habits if more often. * If they consume sweetened beverages (artificial or regular) or sweetened coffee or tea, consume allulose sweetened beverages in place of their artificial or regular sweetened beverages (provided commercial and/or syrups), and sweeten coffee or tea with the provided allulose sweetener. Do this according to usual habits.

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