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Effects of Subconcussive Head Impacts on Neural Integrity and Function in ADHD

N/A
Waitlist Available
Research Sponsored by Indiana University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up blood samples will be collected at pre- and 24 hour post-heading
Awards & highlights
No Placebo-Only Group

Summary

This trial examines how heading a soccer ball affects college-aged players with and without ADHD. Participants will head a soccer ball multiple times, and researchers will use blood tests, brain scans, and eye tests to see how their brains are affected.

Eligible Conditions
  • ADHD
  • Sports Injuries

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~mri procedures will be performed at pre and 24 hour post-heading
This trial's timeline: 3 weeks for screening, Varies for treatment, and mri procedures will be performed at pre and 24 hour post-heading for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Acute change in axonal microstructure from pre to 2 hour post-heading.
Acute Coryza
Acute change in brain-derived blood biomarkers from pre to 2 hour post-heading
+3 more
Secondary study objectives
Acute change in ocular-motor function from pre to 2 hour post-heading
Acute change in ocular-motor function from pre to 24 hour post-heading

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: No history or current diagnosis of ADHD and subconcussive head impactsExperimental Treatment1 Intervention
Non-ADHD Group: Individuals with no current or prior diagnosis of ADHD. Device: Soccer Heading Soccer Heading: Subjects stood approximately 40 feet away from a JUGS soccer ball launcher and participated in 20 consecutive soccer headings, separated by one minute intervals.
Group II: ADHD diagnosis and subconcussive head impactsExperimental Treatment1 Intervention
ADHD Group: Individuals clinically diagnosed with ADHD, currently taking his/her prescribed ADHD medication. Device: Soccer Heading Soccer Heading: Subjects stood approximately 40 feet away from a JUGS soccer ball launcher and participated in 20 consecutive soccer headings, separated by one minute intervals.

Find a Location

Who is running the clinical trial?

Indiana UniversityLead Sponsor
1,045 Previous Clinical Trials
1,316,815 Total Patients Enrolled
~15 spots leftby Dec 2025