High Sodium Diet for Hypernatremia

Recruiting in Palo Alto (17 mi)

Overseen byDavid G Edwards, PhD

Age: 18 - 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Recruiting

Sponsor: University of Delaware

Trial Summary

What is the purpose of this trial?

High sodium diets impair vascular function, which may influence the work of the heart. This investigation is designed to determine if this change in vascular function results in a greater workload in the heart and if people who regularly exercise are protected from these effects.

Eligibility Criteria

This trial is for healthy adults aged 21-45 who are either not very active (exercising at most once a week) or very active (exercising four or more days a week). People with certain health conditions, pregnant women, nursing mothers, smokers, and those outside the specified body mass index range cannot participate.

Inclusion Criteria

I am between 21-45 years old and either mostly inactive or very active.

Exclusion Criteria

Your blood pressure is too high, with the top number (systolic) above 140 and/or the bottom number (diastolic) above 90.

You exercise between 1 to 3 days a week on a regular basis.

I have undergone hormone therapy in the past.

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Treatment Details

Interventions

High Sodium (Electrolyte Supplement)
Placebo (Other)

Trial OverviewThe study is testing how high sodium diets affect heart workload and blood vessel function. It will also explore if regular exercise offers protection against these effects. Participants will be given either a high sodium diet or a placebo to compare outcomes.

Participant Groups

2Treatment groups

Experimental Treatment

Placebo Group

Group I: High SodiumExperimental Treatment1 Intervention

Consumption of an extra 3900 mg of dietary sodium per day.

Group II: PlaceboPlacebo Group1 Intervention

Control Condition