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Astaxanthin, Exercise Inflammation, Skin Health

N/A
Waitlist Available
Led By David C Nieman, DrPH
Research Sponsored by Appalachian State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from pre-study to post-4 weeks supplementation, and immediately post-exercise, and 1.5 hours-, 3 hours-, and 24 hours-post-exerciseingestion to 8- and 24-hours post-ingestion

Summary

This trial is testing whether taking a supplement called astaxanthin can help people recover better from intense exercise and improve their skin health. Astaxanthin is a natural antioxidant found in algae that gives salmon its pink-red color. The study involves participants running on a treadmill for a long duration and taking the supplement for several weeks to see if it helps with recovery and skin health. Astaxanthin is a powerful antioxidant with numerous health benefits, including protection against oxidative stress, anti-inflammatory properties, and potential therapeutic applications in various diseases.

Eligible Conditions
  • Inflammation
  • Metabolic Disorders
  • Immunosuppression

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from pre-study to post-4 weeks supplementation, and immediately post-exercise, and 1.5 hours-, 3 hours-, and 24 hours-post-exerciseingestion to 8- and 24-hours post-ingestion
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from pre-study to post-4 weeks supplementation, and immediately post-exercise, and 1.5 hours-, 3 hours-, and 24 hours-post-exerciseingestion to 8- and 24-hours post-ingestion for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Plasma lipid mediators
Secondary study objectives
Plasma cytokine panel
Plasma proteins

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: AstaxanthinExperimental Treatment1 Intervention
The astaxanthin capsules will contain 8 mg of astaxanthin from freshwater algae in starch beadlets. Ingested daily for 4 weeks.
Group II: PlaceboPlacebo Group1 Intervention
The placebo capsules will contain just the starch beadlets with natural red coloring from the pitaya fruit. Ingested daily for 4 weeks.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Astaxanthin
2014
Completed Phase 3
~430

Find a Location

Who is running the clinical trial?

LycoRed Ltd.Industry Sponsor
12 Previous Clinical Trials
680 Total Patients Enrolled
2 Trials studying Inflammation
50 Patients Enrolled for Inflammation
Appalachian State UniversityLead Sponsor
44 Previous Clinical Trials
2,498 Total Patients Enrolled
14 Trials studying Inflammation
555 Patients Enrolled for Inflammation
David C Nieman, DrPHPrincipal InvestigatorAppalachian State Univ
15 Previous Clinical Trials
899 Total Patients Enrolled
5 Trials studying Inflammation
212 Patients Enrolled for Inflammation
~6 spots leftby Dec 2025
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