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Coating

Ocular Effects of Scleral Lens Wear on Dry Eye Patients

N/A
Waitlist Available
Led By Lyndon Jones, PhD, FCOptom
Research Sponsored by University of Waterloo
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up after 4 weeks of wear of coated lens

Summary

This trial is testing two types of scleral contact lenses on people with dry eyes. One type has a special coating to keep the lenses moist, and the other does not. The study will see how these lenses affect eye dryness, comfort, and vision over a period of time.

Eligible Conditions
  • Dry Eye Syndrome

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~after 4 weeks of wear of uncoated lens
This trial's timeline: 3 weeks for screening, Varies for treatment, and after 4 weeks of wear of uncoated lens for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Contact Lens Dry Eye Questionnaire (CLDEQ-8) Score
Contact Lens Impact on Quality of Life (CLIQ) questionnaire score
Inflammatory marker level in tear film
+2 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Coated Scleral LensExperimental Treatment1 Intervention
Participants wear a lens coated with Hydra-PEG.
Group II: Uncoated Scleral LensPlacebo Group1 Intervention
Participants wear an uncoated (control) lens.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Hydra-PEG
2021
N/A
~30

Find a Location

Who is running the clinical trial?

University of WaterlooLead Sponsor
127 Previous Clinical Trials
214,808 Total Patients Enrolled
Lyndon Jones, PhD, FCOptomPrincipal InvestigatorUniversity of Waterloo
12 Previous Clinical Trials
442 Total Patients Enrolled
~6 spots leftby Dec 2025