← Back to Search

Exercise During Dialysis for Hemodialysis Patients

N/A

Recruiting

Led By Clara Bohm, MD, MPH

Research Sponsored by University of Manitoba

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Must not have

Symptomatic hypoglycemia (>2x/week in week prior to enrolment)

Unstable arrhythmia

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline to 16 weeks

Awards & highlights

No Placebo-Only Group

Summary

This trial will test if cycling during dialysis can reduce heart damage from dialysis in adults.

Who is the study for?

This trial is for adults over 18 who've been on hemodialysis for at least 3 months, with no major changes in their treatment expected. They must be cleared to exercise by a kidney doctor and able to communicate in English. People with recent heart issues, unstable heart rhythms, severe breathlessness, frequent low blood sugar episodes or those already doing similar cycling exercises can't join.

What is being tested?

The study tests if cycling during dialysis sessions over 12 weeks affects the temporary weakening of the heart muscle that sometimes happens after hemodialysis (myocardial stunning). Participants will cycle while undergoing their regular dialysis treatments.

What are the potential side effects?

While not explicitly stated, potential side effects may include muscle soreness, fatigue from exercise during dialysis sessions or exacerbation of existing health conditions due to physical activity.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I have had low blood sugar symptoms more than twice a week recently.

Select...

I do not have an irregular heartbeat that changes often.

Select...

I experience severe shortness of breath even when resting.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline to 16 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline to 16 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 16 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in number of cardiac RWMA at peak hemodialysis stress (last 30 min HD) from baseline to 12 weeks measured using echocardiography

Secondary study objectives

Change in Cognitive Function

Change in Exercise Capacity

Change in Physical Activity Behaviour Patterns

+10 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Exercise (Intradialytic Cycling)Experimental Treatment1 Intervention

Participants will receive a standardized baseline exercise counseling session as per control and then participate in a supervised intradialytic cycling program for 12-weeks

Group II: Usual CareActive Control1 Intervention

Participants will receive a standardized baseline exercise counseling session. Participants in the control group will not undergo formal exercise intervention, but will not be prohibited from participating in exercise outside of hemodialysis. They will be asked to not to participate in intradialytic cycling during the study (16 weeks total).

0 / 3Eligibility criteria met