Palliative Care + Standard Leukemia Care for Acute Myeloid Leukemia

Recruiting in Palo Alto (17 mi)

+3 other locations

Overseen byAreej El-Jawahri, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Massachusetts General Hospital

No Placebo Group

Approved in 4 Jurisdictions

Trial Summary

What is the purpose of this trial?

This research study is evaluating the impact a collaborative palliative care and oncology team will have on the quality of life, symptoms, mood, and end of life outcomes of patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Palliative care is a medical specialty focused on lessening (or "palliating") symptoms and assisting in coping with serious illness.

Eligibility Criteria

This trial is for patients 60 years or older with newly diagnosed acute myeloid leukemia (AML), including those with a history of hematologic disorders, therapy-related AML, relapsed or primary refractory AML. It's also open to hospitalized high-risk AML patients. Those with severe psychiatric illness, other major comorbid conditions, acute promyelocytic leukemia (APML), or already in palliative care cannot participate.

Inclusion Criteria

My AML did not respond to initial treatment.

My AML cancer has returned after treatment.

I have been recently diagnosed with AML caused by previous cancer treatment.

See 2 more

Exclusion Criteria

Major psychiatric illness or comorbid conditions prohibiting compliance with study procedures

I am currently receiving palliative care.

I have been diagnosed with acute promyelocytic leukemia.

Treatment Details

Interventions

Palliative Care (Behavioural Intervention)

Trial OverviewThe study is testing the effects of combining palliative care—a specialty aimed at easing symptoms and helping cope with serious illness—with standard leukemia treatment on quality of life, symptom management, mood, and end-of-life outcomes in AML patients.

Participant Groups

2Treatment groups

Experimental Treatment

Active Control

Group I: Collaborative Palliative and Oncology CareExperimental Treatment1 Intervention

Collaborative care from Palliative Care and Leukemia will be given

Group II: Standard Leukemia CareActive Control1 Intervention

Standard Leukemia care