Cancer Screening for Lung Cancer

Recruiting in Palo Alto (17 mi)

Overseen by Christine D Berg

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: National Cancer Institute (NCI)

No Placebo Group

Approved in 6 Jurisdictions

Trial Summary

What is the purpose of this trial?

This clinical trial studies whether screening methods used to diagnose cancer of the prostate, lung, colon, rectum, or ovaries can reduce deaths from these cancers. Screening tests may help doctors find cancer cells early and plan better treatment for lung cancer.

Eligibility Criteria

This trial is for older individuals who may be at risk of lung cancer. Participants will undergo screening methods to detect any signs of cancer early on, which could lead to better treatment outcomes.

Participant Groups

The study is testing the effectiveness of a screening questionnaire and X-ray imaging in identifying lung cancer in its early stages, with the goal of reducing mortality from this disease.

Group I: Lung Screening Active Control 2 Interventions

Participants undergo a chest x-ray (one postero-anterior view) at baseline and annually for 2 years. Participants classified as "smokers" undergo an additional chest x-ray at year 3. Participants complete a BQF/M at baseline. Participants complete a DQX at baseline and DHQ at year 3. An ADU (previously referred to as the PSH questionnaire) is mailed to each participant annually for 13 years to identify all prevalent and incident lung cancers as all deaths that occur among both screened and control subjects during the trial.

Group II: Control Active Control 1 Intervention

Participants receive standard medical care. Participants complete a DHQ at baseline.

X-Ray Imaging is already approved in European Union, United States, Canada, Japan, China, Switzerland for the following indications:

🇪🇺 Approved in European Union as X-Ray Imaging for:

• Diagnostic imaging for various medical conditions, including pelvic sarcomas

🇺🇸 Approved in United States as X-Ray Imaging for:

• Diagnostic imaging for various medical conditions, including pelvic sarcomas

🇨🇦 Approved in Canada as X-Ray Imaging for:

• Diagnostic imaging for various medical conditions, including pelvic sarcomas

🇯🇵 Approved in Japan as X-Ray Imaging for:

• Diagnostic imaging for various medical conditions, including pelvic sarcomas

🇨🇳 Approved in China as X-Ray Imaging for:

• Diagnostic imaging for various medical conditions, including pelvic sarcomas

🇨🇭 Approved in Switzerland as X-Ray Imaging for:

• Diagnostic imaging for various medical conditions, including pelvic sarcomas

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

National Institutes of Health Clinical Center Bethesda, MD

Who Is Running the Clinical Trial?

National Cancer Institute (NCI) Lead Sponsor

References