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A Feasibility Study Using Four-Dimensional CT Imaging for Primary Lung Cancer

N/A
Waitlist Available
Led By Neal E Dunlap, MD
Research Sponsored by University of Louisville
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years post-treatment
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing whether using a 4D-CT to plan radiation therapy for lung cancer patients results in better outcomes. Patients will have another 4D-CT at 3 and 6 months after treatment to see if there are any changes.

Eligible Conditions
  • Lung Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years post treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years post treatment for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
validate lung strain modeling using 4D-CT in a lung cancer patient population to correlate pre-treatment strain with post-treatment changes.
Secondary study objectives
correlate 4D-CT based lung strain modeling with standard lung function studies including pulmonary function tests and ventilation-perfusion scans.
correlate post-treatment strain with radiographic changes to the lung parenchyma
correlate pre- and post-treatment strain with clinical toxicity

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Study ArmExperimental Treatment1 Intervention
Single Arm

Find a Location

Who is running the clinical trial?

James Graham Brown Cancer CenterOTHER
43 Previous Clinical Trials
9,161 Total Patients Enrolled
University of LouisvilleLead Sponsor
348 Previous Clinical Trials
77,666 Total Patients Enrolled
Neal E Dunlap, MDPrincipal InvestigatorJames Graham Brown Cancer Center
2 Previous Clinical Trials
64 Total Patients Enrolled
~3 spots leftby Dec 2025
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