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uEXPLORER vs Conventional PET/CT Imaging for Cancer

N/A

Waitlist Available

Led By Lorenzo Nardo, MD

Research Sponsored by University of California, Davis

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Diagnosis or suspected diagnosis of lung cancer, melanoma or lymphoma.

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up one imaging visit up to two hours

Awards & highlights

No Placebo-Only Group

Summary

This trial will compare the image quality of two types of PET/CT scans to see which one requires the shorter scan duration.

Who is the study for?

This trial is for men and women over 18 who can consent to participate, have or might have lung cancer, lymphoma, or melanoma, and need a PET/CT scan. It's not for pregnant individuals, those with claustrophobia, or anyone with a condition that could affect their safety in the study.

What is being tested?

The trial is testing if shorter scans using a new total-body PET/CT scanner (uEXPLORER) are as good as longer ones on conventional scanners for patients with lung cancer, lymphoma, or melanoma. Participants will undergo both types of scans.

What are the potential side effects?

Since this trial involves imaging techniques rather than drugs, side effects may include discomfort from lying still during the scan and potential reactions to contrast agents used in imaging.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have or may have lung cancer, melanoma, or lymphoma.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ one imaging visit up to two hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~one imaging visit up to two hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and one imaging visit up to two hours for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Minimum scan duration on a total-body PET/CT scanner for quality

Secondary study objectives

Minimum scan duration on a total-body PET/CT scanner for tumor recognition

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Group I: uEXPLORER/mCTExperimental Treatment1 Intervention

Each patient will undergo a scan on a total-body PET/CT scanner (uEXPLORER) and then undergo an additional scan on a conventional PET/CT scanner (mCT). The first scan will take place 60 minutes after injection with 18F-FDG and the second scan will be 90 minutes after injection with 18F-FDG.

Group II: mCT/uEXPLORERExperimental Treatment1 Intervention

Each patient will undergo a scan on a conventional PET/CT scanner (mCT) and then undergo an additional scan on a total-body PET/CT scanner (uEXPLORER) . The first scan will take place 60 minutes after injection with 18F-FDG and the second scan will be 90 minutes after injection with 18F-FDG.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

uEXPLORER/mCT

2021

N/A

~20

0 / 1Eligibility criteria met