~131 spots leftby Apr 2026

The MitraClip® EXPAND Study of the Next Generation of MitraClip® Devices

Recruiting in Palo Alto (17 mi)
+73 other locations
PF
DS
Overseen byDr. Saibal Kar, MD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Abbott Medical Devices
No Placebo Group

Trial Summary

What is the purpose of this trial?

The MitraClip EXPAND Study (A Contemporary, Prospective Study Evaluating Real-world Experience of Performance and Safety for the Next Generation of MitraClip Devices) is designed to confirm the safety and performance of the MitraClip NTR System and MitraClip XTR System.

Research Team

PF

Prof. Francesco Maisano, MD

Principal Investigator

University Hospital, Zürich

DS

Dr. Saibal Kar, MD

Principal Investigator

Cedars Sinai, Los Angeles CA

Eligibility Criteria

Inclusion Criteria

Subjects who give consent for their participation
Subjects scheduled to receive the MitraClip per the current approved indications for use
Subjects with Symptomatic MR (≥3+)

Treatment Details

Interventions

  • MitraClip NTR/XTR System (Device)
Participant Groups
1Treatment groups
Experimental Treatment
Group I: MitraClip NTR/XTR SystemExperimental Treatment1 Intervention
Percutaneous mitral valve repair using the MitraClip NTR and XTR system

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
St. Thomas HospitalNashville, TN
Baptist Medical Center PrincetonBirmingham, AL
Atlantic Health System - Morristown Memorial HospitalMorristown, NJ
University of ColoradoAurora, CO
More Trial Locations
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Who Is Running the Clinical Trial?

Abbott Medical Devices

Lead Sponsor

Trials
659
Patients Recruited
420,000+
Founded
1888
Headquarters
Abbott Park, Illinois, USA
Known For
Medical Devices Innovation
Top Products
FreeStyle Libre, MitraClip, XIENCE Stents, TECNIS IOLs

Abbott

Industry Sponsor

Trials
760
Patients Recruited
489,000+