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Exercise for Multiple Sclerosis
N/A
Recruiting
Led By Cameron Mang, PhD
Research Sponsored by University of Regina
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 weeks post intervention
Summary
This trial will compare the effects of different types of exercise on physical function, fitness, and central nervous system function in people with progressive MS.
Who is the study for?
This trial is for people with progressive multiple sclerosis (MS) who have moderate motor disability and can safely exercise. They should not be highly active already, haven't had an MS relapse in the last three months, and don't have other neurological conditions, psychiatric diagnoses or substance abuse issues.
What is being tested?
The study is testing how different types of exercises affect physical function, fitness, and central nervous system changes in individuals with MS. Participants will be assigned to one of three distinct exercise protocols to see which has the most beneficial effects.
What are the potential side effects?
Since this trial involves exercise programs rather than medication, side effects may include typical exercise-related discomforts such as muscle soreness or fatigue. However, specific risks depend on each participant's condition.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 6 weeks post intervention
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 weeks post intervention
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Timed 25-Foot Walk Test
Secondary study objectives
Motor Evoked Potential Amplitude
Other study objectives
9-Hole Pegboard Test
Brain
Mini Balance Evaluation Systems Test
+7 moreTrial Design
3Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: Exercise Group 1Experimental Treatment1 Intervention
The intervention will focus on mobility and balance.
Group II: Exercise Group 2Active Control1 Intervention
This intervention will focus on physical fitness.
Group III: Exercise Group 3Placebo Group1 Intervention
This intervention will focus on flexibility, range of motion, and muscle tone.
Find a Location
Who is running the clinical trial?
University of ReginaLead Sponsor
56 Previous Clinical Trials
8,927 Total Patients Enrolled
First Steps Wellness CentreUNKNOWN
Saskatchewan Health Research FoundationOTHER
32 Previous Clinical Trials
5,065 Total Patients Enrolled
University of SaskatchewanOTHER
257 Previous Clinical Trials
156,022 Total Patients Enrolled
5 Trials studying Multiple Sclerosis
35,250 Patients Enrolled for Multiple Sclerosis
Cameron Mang, PhDPrincipal InvestigatorUniversity of Regina
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have never had a seizure or other reasons I can't have TMS.I have been diagnosed with progressive MS by a neurologist.My condition is progressive MS, diagnosed by a neurologist.I have had a relapse in the last 3 months, confirmed by my neurologist.I have a neurological condition that is not multiple sclerosis.I have moderate difficulty moving around due to my condition.It takes me more than 6 seconds to walk 25 feet.
Research Study Groups:
This trial has the following groups:- Group 1: Exercise Group 1
- Group 2: Exercise Group 2
- Group 3: Exercise Group 3
Awards:
This trial has 0 awards, including:Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Multiple Sclerosis Patient Testimony for trial: Trial Name: NCT05496881 — N/A