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Quad Tendon vs BTB Graft for ACL Reconstruction

N/A
Recruiting
Led By Amit Momaya, MD
Research Sponsored by University of Alabama at Birmingham
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights
No Placebo-Only Group

Summary

This trial is comparing two methods of ACL reconstruction - a quad tendon graft with a bone plug, and a patellar tendon graft - to see which is more effective.

Who is the study for?
This trial is for skeletally mature individuals under 40 with an ACL injury who are scheduled for autograft reconstruction. It's not suitable for those unlikely to follow physical therapy, needing multiple ligament reconstructions, or wanting to return to sports within 6 months. Pregnant or nursing persons can't join.
What is being tested?
The study compares two types of knee surgery grafts: the quad tendon (all soft tissue) and the patellar tendon (with bone). This randomized controlled trial aims to determine which graft option is better for ACL reconstruction.
What are the potential side effects?
Potential side effects may include pain at the graft site, swelling, infection risk, stiffness in the knee joint, difficulty regaining full range of motion and strength in the affected leg.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
KT-1000 Arthrometer
Secondary study objectives
ACL Return to Sport Index (ACL-RSI)
International Knee Documentation Committee (IKDC) Knee Evaluation Form
Knee Injury and Osteoarthritis Outcome Score (KOOS)
+5 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Active Control
Group I: Quad tendonActive Control1 Intervention
ACL graft harvested from the quadriceps tendon
Group II: BTB tendonActive Control1 Intervention
ACL graft harvested from the patellar tendon

Find a Location

Who is running the clinical trial?

University of Alabama at BirminghamLead Sponsor
1,656 Previous Clinical Trials
2,444,275 Total Patients Enrolled
Amit Momaya, MDPrincipal InvestigatorDepartment of Orthopaedic Surgery, University of Alabama at Birmingham
3 Previous Clinical Trials
148 Total Patients Enrolled

Media Library

BTB (Other) Clinical Trial Eligibility Overview. Trial Name: NCT05461326 — N/A
Anterior Cruciate Ligament Injury Research Study Groups: Quad tendon, BTB tendon
Anterior Cruciate Ligament Injury Clinical Trial 2023: BTB Highlights & Side Effects. Trial Name: NCT05461326 — N/A
BTB (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05461326 — N/A
~55 spots leftby Jun 2026