Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors

Recruiting in Palo Alto (17 mi)

+155 other locations

Overseen BySmita Bhatia

Age: Any Age

Sex: Any

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Children's Oncology Group

No Placebo Group

Trial Summary

What is the purpose of this trial?This clinical trial studies cancer survivors to identify those who are at increased risk of developing late-occurring complications after undergoing treatment for childhood cancer. A patient's genes may affect the risk of developing complications, such as congestive heart failure, avascular necrosis, stroke, and second cancer, years after undergoing cancer treatment. Genetic studies may help doctors identify survivors of childhood cancer who are more likely to develop late complications.

Eligibility Criteria

Participant Groups

1Treatment groups

Experimental Treatment

Group I: Observational (genetic analysis)Experimental Treatment2 Interventions

DNA from peripheral blood or saliva sample of patients is analyzed for the presence of polymorphisms in genes associated with an increased risk of late-occurring complications.