Magnetic Resonance Elastography for Brain Cancer

N/A

Waitlist Available

Led By Mark S Shiroishi, MD

Research Sponsored by University of Southern California

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline to 6 weeks

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing whether magnetic resonance elastography (MRE) can help determine the consistency of brain tumors and whether this information could be used to guide surgical planning for patients with brain tumors.

Who is the study for?

This trial is for adults over 18 with brain tumors who are scheduled for surgical removal at Keck Medical Center of USC. It's not suitable for those unable to undergo MRE or MRI, including individuals with metal implants, claustrophobia, a large body size, minors, pregnant women, state wards, and prisoners.

What is being tested?

The study is testing magnetic resonance elastography (MRE), a new imaging technique to measure brain tumor consistency. This will be compared with standard MRI scans to see if it can improve surgical planning.

What are the potential side effects?

Since the intervention involves non-invasive imaging techniques like MRE and MRI rather than drugs or surgery, side effects are minimal but may include discomfort from lying still during the scan or reactions in those with claustrophobia.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline to 6 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline to 6 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 6 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Tumor stiffness (based on MRE)

Hantavirus Pulmonary Syndrome

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Diagnostic (MRE, tumor grading)Experimental Treatment2 Interventions

Patients undergo MRE scan over 25 minutes before surgery at the time of standard of care pre-operative MRI scan. On the day of surgery, the surgeon grades and records tumor consistency/stiffness during the operation and afterwards.

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