Brain Activity Study for Anxiety Disorder

N/A

Recruiting

Led By Mohammed Milad, PhD

Research Sponsored by The University of Texas Health Science Center, Houston

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Must not have

History of neurologic disease

History of seizure or significant head trauma/loss of consciousness

Timeline

Screening 3 weeks

Treatment Varies

Follow Up immediately after the memory recall phase (day 2 about 1 day 18 minutes after start of memory recall phase).

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to study brain activity related to fear conditioning, avoidance learning, and memory recall. Researchers will investigate how different brain waves and connections in the brain are involved in these processes. They will also

Who is the study for?

This trial is for individuals with an anxiety disorder. Participants should be able to undergo fear conditioning and active avoidance tasks while their brain activity is monitored using EEG. Specific inclusion or exclusion criteria are not provided, but typically participants must be healthy enough for the procedures.

What is being tested?

The study investigates how certain brain wave patterns (ERPs and EROs) relate to learning about fear and making decisions to avoid things that cause fear. It uses a special task called CAAP while recording brain activity with EEG, looking at memory recall related to fear and avoidance.

What are the potential side effects?

Since this study involves non-invasive monitoring of brain activity through EEG during specific tasks, there are minimal side effects expected. Some participants might experience discomfort from wearing the EEG cap or stress from the fear-conditioning exercises.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I have a history of a neurological condition.

Select...

I have had a seizure or significant head injury.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ immediately after the memory recall phase (day 2 about 1 day 18 minutes after start of memory recall phase)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~immediately after the memory recall phase (day 2 about 1 day 18 minutes after start of memory recall phase)

This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately after the memory recall phase (day 2 about 1 day 18 minutes after start of memory recall phase) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Number of participants who had higher event-related potentials (ERPs) in response to CS+ categories relative to CS- categories, as assessed by electroencephalogram (EEG) during the avoidance learning phase

+9 more